SAB5701000

Anti-DDB2 antibody produced in rabbit

• 分類程式碼代碼: 12352203
• NACRES: NA.41
• 無性繁殖: monoclonal
• application: WB
• 物種活性: human, mouse
• 技術: western blot: 1:500-1:2000

屬性

• 生物源: rabbit
• 品質等級: 100
• 抗體產品種類: primary antibodies
• 無性繁殖: monoclonal
• 形狀: liquid
• 物種活性: human, mouse
• 濃度: 0.4 mg/mL
• 技術: western blot: 1:500-1:2000
• UniProt登錄號: Q92466
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... DDB2(1643)

描述

一般說明

This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

免疫原

A synthesized peptide derived from human DDB2

外觀

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable