SAB5700472

Anti-Phospho-PLCG2-Y1217 antibody produced in rabbit

• 同義詞: APLAID, FCAS3, PLC-IV, PLC-gamma-2, PLCG2
• 分類程式碼代碼: 12352203

屬性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: 147
• 物種活性: mouse, human
• 濃度: 0.37 mg/ml
• 技術: immunohistochemistry: 1:50-1:200; western blot: 1:500-1:2000
• UniProt登錄號: P16885
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: phosphorylation (pTyr1217)
• 基因資訊: human ... PLCG2(5336)

描述

一般說明

The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.

免疫原

A synthetic phosphorylated peptide around Y1217 of human PLCG2 (NP_002652.2).

外觀

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

儲存和穩定性

Store at -20℃. Avoid freeze / thaw cycles.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable