SAB5700387

Anti-Phospho-p38 MAPK-T180/Y182 antibody produced in rabbit

• 同義詞: CSBP, CSBP1, CSBP2, CSPB1, EXIP, MAPK14, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38 MAPK, p38ALPHA
• 分類程式碼代碼: 12352203
• NACRES: NA.43

屬性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: 29; 34; 35; 41
• 物種活性: mouse, human, rat
• 濃度: 5.56 mg/ml
• 技術: immunofluorescence: 1:50-1:200; western blot: 1:500-1:2000
• UniProt登錄號: Q16539
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: phosphorylation (pThr180/pTyr182)
• 基因資訊: human ... MAPK14(1432)

描述

一般說明

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

免疫原

A synthetic phosphorylated peptide around T180 & Y182 of human p38 MAPK (NP_620581.1).

外觀

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

儲存和穩定性

Store at -20℃. Avoid freeze / thaw cycles.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable