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Key Documents

SAB5200109

Sigma-Aldrich

Anti-AQP1 antibody produced in rabbit

1 mg/mL, affinity isolated antibody

同義詞:

Anti-AQP1, Anti-Aquaporin 1, Anti-Water channel protein CHIP29

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous glycerol solution

分子量

antigen predicted mol wt 28.5 kDa

物種活性

mouse, human, rat

濃度

1 mg/mL

技術

indirect immunofluorescence: suitable
western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

rat ... Aqp1(25240)

一般說明

Aquaporin 1 (AQP1) is expressed in the nervous system. The gene ID of the protein is 25240.

特異性

Detects ~28.5 kDa. May detect larger glycosylated bands ~35-50 kDa.

免疫原

N-terminal peptide

生化/生理作用

Aquaporin 1 (AQP1) aids in transporting water across cell membranes. It also contributes to the migration and proliferation of pulmonary arterial smooth muscle cells.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

PBS, pH 7..4, 50% glycerol, and 0.09% sodium azide

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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E Segura-Anaya et al.
Neuroscience, 285, 119-127 (2014-12-03)
Aquaporin 1 (AQP1) is a member of a family of small, integral membrane water-transporting proteins, which facilitate water movement across cell membranes in response to osmotic gradients. Several papers have studied the expression and function of the AQPs in the
Ning Lai et al.
American journal of respiratory cell and molecular biology, 50(6), 1010-1020 (2013-12-18)
Pulmonary arterial smooth muscle cell (PASMC) proliferation and migration are important contributors to the vascular remodeling that occurs during development of pulmonary hypertension. We previously demonstrated that aquaporin (AQP)1, a member of the water channel family of proteins, was expressed
Y L Yu et al.
Biomaterials, 35(25), 6822-6828 (2014-05-27)
Renal regeneration approaches offer great potential for the treatment of chronic kidney disease, but their availability remains limited by the clinical challenges they pose. In the present study, we used continuous detergent perfusion to generate decellularized (DC) rat kidney scaffolds.
Tomoko Iida et al.
Clinical and experimental nephrology, 18(3), 432-443 (2013-07-19)
Several proteins have been proposed as new urinary biomarkers of kidney injuries, but they are not always capable of identifying the kidney nephron segment that has been injured. Since calbindin 1 protein is exclusively localized in the kidney distal nephron
Dieanira Erudaitius et al.
PloS one, 12(1), e0170442-e0170442 (2017-01-21)
Cancer cell toxicity to therapeutic H2O2 varies widely depending on cell type. Interestingly, it has been observed that different cancer cell types have varying peroxiporin expression. We hypothesize that variation in peroxiporin expression can alter cell susceptibility to therapeutic H2O2

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