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Key Documents

SAB5200047

Sigma-Aldrich

Monoclonal Anti-SHANK3 antibody produced in mouse

clone S72-16, 1 mg/mL, purified immunoglobulin

同義詞:

Anti-Prosap2, Anti-SHANK3, S69-46, Anti-Shank3

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

mouse

共軛

unconjugated

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

S72-16, monoclonal

形狀

buffered aqueous glycerol solution

分子量

antigen predicted mol wt 190 kDa

物種活性

mouse, rat, human

濃度

1 mg/mL

技術

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

特異性

Detects ~190 kDa. No cross-reactivity against Shank1 or Shank2.

免疫原

Synthetic peptide amino acids 840-857 of rat Shank3, Accession Number Q9JLU4

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Solution in PBS, pH 7.4, 50% glycerol, and 0.09% sodium azide

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Meghan Kerrisk Campbell et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 38(23), 5289-5301 (2018-05-08)
Mutations or altered protein levels of SHANK3 are implicated in neurodevelopmental disorders such as Phelan-McDermid syndrome, autism spectrum disorders, and schizophrenia (Guilmatre et al., 2014). Loss of SHANK3 in mouse models results in decreased synapse density and reduction in the

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