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重要文件

SAB5200006

Sigma-Aldrich

Monoclonal Anti-CRYAA antibody produced in mouse

clone 1H3.B8, 1 mg/mL, purified immunoglobulin

同義詞:

Anti-Acry1, Anti-Alpha A Crystallin, Anti-CRYA1, Anti-CRYAA, Anti-Heat Shock protein beta4, Anti-HspB4

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

mouse

品質等級

共軛

unconjugated

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

1H3.B8, monoclonal

形狀

buffered aqueous glycerol solution

分子量

antigen predicted mol wt 20 kDa

物種活性

bovine, rat, mouse, human

濃度

1 mg/mL

技術

indirect ELISA: suitable
western blot: suitable

同型

IgG1

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... CRYAA(1409)

特異性

Detects α-crystallin at ~20 kDa. Does not cross-react with αB-crystallin, βL-crystallin, βH- crystallin, γ-crystallin, Hsp25, Hsp27 or Hsp47 proteins.

免疫原

Native Alpha Crystallin

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Solution in PBS, pH 7.2, in 50% glycerol, and 0.09% sodium azide

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

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Shiwani Sharma et al.
Molecular vision, 24, 801-817 (2019-02-05)
Pseudoexfoliation (PEX) syndrome is an age-related progressive disease of the extracellular matrix with ocular manifestations. PEX is clinically diagnosed by the presence of extracellular exfoliative deposits on the anterior surface of the ocular lens. PEX syndrome is a major risk
Xiang-Jia Zhu et al.
Journal of cellular and molecular medicine, 22(2), 1118-1126 (2017-10-11)
Post-translational modifications in lens proteins are key causal factors in cataract. As the most abundant post-translational modification in the lens, racemization may be closely related to the pathogenesis of cataract. Racemization of αA-crystallin, a crucial structural and heat shock protein
Andrea Schlotterer et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(3), 4141-4153 (2018-11-30)
The aim of this study was to evaluate whether damage to the neurovascular unit in diabetes depends on reactive metabolites such as methylglyoxal (MG), and to assess its impact on retinal gene expression. Male Wistar rats were supplied with MG
Jason Tchieu et al.
Cell stem cell, 21(3), 399-410 (2017-09-09)
Directing the fate of human pluripotent stem cells (hPSCs) into different lineages requires variable starting conditions and components with undefined activities, introducing inconsistencies that confound reproducibility and assessment of specific perturbations. Here we introduce a simple, modular protocol for deriving

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