推薦產品
product name
抗- 胶质纤维酸性蛋白抗体，小鼠单克隆, clone G-A-5, purified from hybridoma cell culture
生物源
mouse
品質等級
共軛
unconjugated
抗體表格
purified from hybridoma cell culture
purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
G-A-5, monoclonal
形狀
buffered aqueous solution
分子量
antigen ~50 kDa
物種活性
rat, human, pig
濃度
~1.0 mg/mL
技術
immunocytochemistry: suitable
immunohistochemistry: suitable
indirect immunofluorescence: 2.5-5 μg/mL using alcohol-fixed sections of rat brain/cerebellum.
western blot: suitable
同型
IgG1
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... GFAP(2670)
mouse ... Gfap(14580)
pig ... GFAP(396562)
rat ... Gfap(24387)
一般說明
神经胶质原纤维酸性蛋白（GFAP）是存在于星形胶质细胞中的中间丝，以10种不同的亚型进行表达。它由N端头部、中心杆和C端尾部结构域组成。GFAP位于人类染色体17q21.33。
免疫原
纯化的猪脊髓 GFAP。
應用
神经胶质纤维酸性蛋白单克隆抗体适用于蛋白印迹和间接免疫荧光（2.5-5 μg/mL，使用酒精固定的大鼠脑/小脑切片）。该抗体还可用于免疫印迹（约50 kDa）、免疫组化（多聚甲醛固定的兔脑冷冻切片）和免疫细胞化学。
神经胶质纤维酸性蛋白抗体（小鼠单克隆抗体）可用于免疫细胞化学和免疫荧光。
生化／生理作用
神经胶质纤维酸性蛋白或GFAP组装与神经胶质结构的有丝分裂重塑有关。GFAP基因突变与亚历山大病有关。
神经胶质纤维酸性蛋白（GFAP）基因位点的微缺失与儿童智力残疾和面部畸形有关。GFAP水平升高与急性脑出血有关。
外觀
0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
未找到適合的產品？
試用我們的產品選擇工具.
儲存類別代碼
10 - Combustible liquids
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
客戶也查看了
Novel organotypic in vitro slice culture model for intraventricular hemorrhage of premature infants.
Govindaiah Vinukonda et al.
Journal of neuroscience research, 90(11), 2173-2182 (2012-07-19)
Mechanisms of brain injury in intraventricular hemorrhage (IVH) of premature infants are elusive, and no therapeutic strategy exists to prevent brain damage in these infants. Therefore, we developed an in vitro organotypic forebrain slice culture model to advance mechanistic studies
Yun Chen et al.
Journal of neuroimmunology, 334, 576978-576978 (2019-06-10)
Alzheimer's disease (AD) is a common neurodegenerative disorder characterized by progressive learning and cognitive damage. Several hypotheses such as amyloid cascade hypothesis, hyper-phosphorylated τ hypothesis, and energy metabolism hypothesis have been proposed to elucidate the disease. However, the exact mechanism
Lipopolysaccharide differentially modulates expression of cytokines and cyclooxygenases in dorsal root ganglion cells via Toll-like receptor-4 dependent pathways
Tse KH, et al.
Neuroscience, 267, 241-2251 (2014)
Advanced Clinical Imaging and Tissue-based Biomarkers of the Eye for Toxicology Studies in Minipigs.
Elke-Astrid Atzpodien et al.
Toxicologic pathology, 44(3), 398-413 (2015-12-19)
There is increased interest to use minipigs in ocular toxicology studies due to their anatomical similarities with human eyes and as a substitute for nonhuman primates. This requires adaptation of enhanced optical coherence tomography (OCT) techniques and of ocular relevant
TWO CASES WITH DIFFERENT EPILEPSY TYPE AND DYSMORPHIC FEATURES ASSOCIATED WITH 17q21. 31 MICRODELETION SYNDROME
Uctepe E, et al.
Genetic Counseling (Geneva, Switzerland), 27(3), 357-365 (2016)
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務