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Key Documents

SAB4700611

Sigma-Aldrich

Monoclonal Anti-FOXP3-PE antibody produced in mouse

clone 3G3, purified immunoglobulin, buffered aqueous solution

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

mouse

共軛

phycoerythrin (R-PE) conjugate

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

3G3, monoclonal

形狀

buffered aqueous solution

物種活性

mouse, human

濃度

0.5 mg/mL

技術

flow cytometry: suitable

同型

IgG1

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

2-8°C

目標翻譯後修改

unmodified

基因資訊

human ... FOXP3(50943)

一般說明

The mouse monoclonal antibody 3G3 recognizes N-terminal region of FoxP3, a 47-55 kDa transcription factor, which is the master regulator in the development and function of regulatory T cells.

免疫原

Full-length His-tagged recombinant murine FoxP3

應用

The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 3 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Solution in phosphate buffered saline containing 15 mM sodium azide

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Yue Ren et al.
International immunology, 26(10), 551-561 (2014-05-24)
NKT cells are characterized by their expression of an NKT-cell-specific invariant antigen-receptor α chain encoded by Vα14Jα18 gene segments. These NKT cells bridge the innate and acquired immune systems to mediate effective and augmented responses; however, the limited number of
Marc A Gavin et al.
Proceedings of the National Academy of Sciences of the United States of America, 103(17), 6659-6664 (2006-04-18)
Forkhead winged-helix transcription factor Foxp3 serves as the dedicated mediator of the genetic program governing CD25+CD4+ regulatory T cell (T(R)) development and function in mice. In humans, its role in mediating T(R) development has been controversial. Furthermore, the fate of

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