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Merck
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重要文件

SAB4504378

Sigma-Aldrich

Anti-phospho-DARPP-32 (pThr34) antibody produced in rabbit

affinity isolated antibody

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen 22 kDa

物種活性

mouse, rat, human

濃度

~1 mg/mL

技術

ELISA: 1:10000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

phosphorylation (pThr34)

基因資訊

human ... PPP1R1B(84152)

相關類別

一般說明

PPP1R1B (protein phosphatase 1 regulatory inhibitor subunit 1B)/DARPP32 (dopamine- and cAMP-regulated phosphoprotein of molecular weight 32 kDa) encodes two transcripts which are further translated into two DARPP-32 protein isoforms, full length (fl)-DARPP-32 and truncated (t)-DARPP. It is located on human chromosome 17q12.

免疫原

The antiserum was produced against synthesized peptide derived from human DARPP-32 around the phosphorylation site of Thr34.

Immunogen Range: 18-67

生化/生理作用

PPP1R1B (protein phosphatase 1 regulatory inhibitor subunit 1B)/DARPP32 (dopamine- and cAMP-regulated phosphoprotein of molecular weight 32 kDa) is considered as an inhibitor of phosphate-1 (PP-1) protein. This protein is associated with working memory and emotion processing.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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存取文件庫

Human t-DARPP is induced during striatal development.
Straccia M, et al.
Neuroscience, 333, 320-330 (2016)
Variation of the gene coding for DARPP-32 (PPP1R1B) and brain connectivity during associative emotional learning.
Curcic-Blake B, et al.
Neuroimage, 59(2), 1540-1550 (2012)
Integrated gene copy number and expression microarray analysis of gastric cancer highlights potential target genes.
Myllykangas S, et al.
International Journal of Cancer. Journal International Du Cancer, 123(4), 817-825 (2008)

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