SAB4504108

Anti-phospho-TIP60 (pSer⁸⁶) antibody produced in rabbit

affinity isolated antibody

• 同義詞: KAT5, Lysine acetyltransferase 5
• 分類程式碼代碼: 12352203
• NACRES: NA.43

屬性

• 生物源: rabbit
• 共軛: unconjugated
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: antigen 58 kDa
• 物種活性: rat, mouse, human
• 濃度: ~1 mg/mL
• 技術: ELISA: 1:40000; western blot: 1:500-1:1000
• NCBI登錄號: Q92993
• UniProt登錄號: Q92993
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: phosphorylation (pSer86)
• 基因資訊: human ... KAT5(10524)

描述

一般說明

The TIP60 (HIV1 (human immunodeficiency virus 1)-TAT interactive protein) gene is mapped to human chromosome 11q13.1. It is ubiquitously expressed and evolutionarily conserved. The encoded protein, Tip60 belongs to the MYST (Moz, Ybf2/Sas3, Sas2 and TIP60) family.

免疫原

The antiserum was produced against synthesized peptide derived from human TIP60 around the phosphorylation site of Ser86.

Immunogen Range: 52-101

應用

TIP60 (HIV1-TATinteractive protein) possess acetyltransferase activity and participates in chromatin remodeling and DNA damage repair. TIP60 is involved in protein stabilization and protein function modulation. The presence of chromodomain and MYST domain in its structure enables acetylation of both histone and non-histone proteins. TIP60 in association with androgenic receptors and transcription factors can control gene transcription and cell cycle process. TIP60 mediates p53 action to induce apoptosis. TIP60 inhibits Hepatitis B virus infection. TIP60 acts as a haploinsufficient tumor suppressor.

特點和優勢

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外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable