SAB4503836

Anti-phospho-STAT2 (pTyr⁶⁹⁰) antibody produced in rabbit

affinity isolated antibody

• 同義詞: Anti-IMD44, Anti-ISGF-3, Anti-P113, Anti-PTORCH3, Anti-STAT113
• 分類程式碼代碼: 12352203
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 100
• 共軛: unconjugated
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: antigen 97 kDa
• 物種活性: human, mouse, rat
• 濃度: ~1 mg/mL
• 技術: ELISA: 1:20000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI登錄號: P52630
• UniProt登錄號: P52630
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: phosphorylation (pTyr690)
• 基因資訊: human ... STAT2(6773)

描述

一般說明

STAT2 (signal transducer and activator of transcription 2) is mapped to human chromosome 12.

Signal transducer and activator of transcription 2 (STAT2) belongs to the STAT family. The gene is located on human chromosome 12q13.3. STAT2 consists of 24 exons and has a molecular weight of 113 kDa. It consists of N-terminal domain (N), coiled-coil domain (CC), DNA-binding domain (DBD), linker domain (L), Src homology 2 domain (SH2), tyrosine phosphorylation site (Y) and transcriptional activation domain (TAD).

免疫原

The antiserum was produced against synthesized peptide derived from human STAT2 around the phosphorylation site of Tyr690.

Immunogen Range: 656-705

應用

Anti-phospho-STAT2 (pTyr690) antibody produced in rabbit has been used in western blotting, immunofluorescence staining and flow cytometric staining.

Anti-phospho-STAT2 (pTyr⁶⁹⁰) antibody produced in rabbit has been used:

• for western blotting
• for immunofluorescence staining
• for flow cytometric staining

生化／生理作用

STAT2 (signal transducer and activator of transcription 2) participates in immunity. It plays a major role in interferon signaling pathways.

Signal transducer and activator of transcription 2 (STAT2) is activated by interferon-1 (IFN-I) and IFN-III. It aids protein-protein interactions and is essential for binding IRF9. STAT2 is required for the nuclear export of STAT2-IFN regulatory factor 9 (IRF9) and IFN-stimulated gene factor 3 (ISGF3). It plays a vital role in interactions with STAT1.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable