SAB4300672

Anti-phospho-Stat2 (pTyr⁶⁹⁰) antibody produced in rabbit

affinity isolated antibody

• 同義詞: Anti-ISGF-3, Anti-MGC59816, Anti-P113, Anti-STAT113
• 分類程式碼代碼: 12352203
• NACRES: NA.41

屬性

• 生物源: rabbit
• 共軛: unconjugated
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: ~113 kDa
• 物種活性: human
• 濃度: 1 mg/mL
• 技術: western blot: 1:500-1:1000
• 同型: IgG
• 免疫原序列: (R-K-Yp-L-K)
• NCBI登錄號: NM_005419.3
• UniProt登錄號: P52630
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: phosphorylation (pTyr690)
• 基因資訊: human ... Stat2(6773)

描述

一般說明

The antibody detects endogenous level of Stat2 only when phosphorylated at Tyrosine 690.

免疫原

Peptide sequence around phosphorylation site of tyrosine 690 (R-K-Yp-L-K), according to the protein NP_005410.1

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

標靶描述

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) hasbeen shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene.

外觀

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable