跳轉至內容
Merck
全部照片(2)

重要文件

SAB4503132

Sigma-Aldrich

Anti-FZD5 antibody produced in rabbit

affinity isolated antibody

同義詞:

FZD5, Frizzled-5, Fz-5, FzE5, hFz5

登入查看組織和合約定價


About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41
無性繁殖:
polyclonal
application:
ELISA
IF
IHC
物種活性:
mouse, human, rat
技術:
ELISA: 1:5000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
citations:
6

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen 64 kDa

物種活性

mouse, human, rat

濃度

~1 mg/mL

技術

ELISA: 1:5000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... FZD5(7855)

相關類別

一般說明

Anti-FZD5 Antibody detects endogenous levels of total FZD5 protein.
The FZD5 (frizzled class receptor 5) gene encodes a receptor FZ5 for Wnt proteins and is mapped to human chromosome 2q33.3.

免疫原

The antiserum was produced against synthesized peptide derived from human FZD5.

Immunogen Range: 31-80

生化/生理作用

Fzd5 (frizzled class receptor 5) is a receptor component for the canonical and non-canonical Wnt signaling pathways which is necessary for cell proliferation and cell differentiation. Fzd5 might serve as an important biomarker for eye malformation. The Wnt5a-Fz5 complex is known to support the functions of innate immunity. Fzd5 along with Gcm1 (chorion-specific transcription factor) is involved in a feedback mechanism that regulates trophoblast differentiation and chorionic branching in placenta.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

未找到適合的產品?  

試用我們的產品選擇工具.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


從最近期的版本中選擇一個:

分析證明 (COA)

Lot/Batch Number

未看到正確版本?

如果您需要一個特定的版本,您可以透過批號來尋找特定憑證。

已經擁有該產品?

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Wnt5a-Rac1-NF-κB homeostatic circuitry sustains innate immune functions in macrophages.
Naskar D, et al.
Journal of Immunology, 192(9), 4386-4397 (2014)
A secreted WNT-ligand-binding domain of FZD5 generated by a frameshift mutation causes autosomal dominant coloboma
Liu C, et al.
Human Molecular Genetics, 25(7), 1382-1391 (2016)
Functional analysis of dishevelled-3 phosphorylation identifies distinct mechanisms driven by casein kinase 1ε and frizzled5.
Bernatik O, et al.
The Journal of Biological Chemistry, 289(34), 23520-23533 (2014)
A Positive Feedback Loop Involving Gcm1 and Fzd5 Directs Chorionic Branching Morphogenesis in the Placenta
Lu J, et al.
PLoS Biology, 11(4), e1001536-e1001536 (2013)
Strong linkage on 2q33.3 to familial early-onset generalized osteoarthritis and a consideration of two positional candidate genes
Meulenbelt I, et al.
European Journal of Human Genetics, 14(12), 1280-1280 (2006)

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務