SAB4501670

Anti-Keratin 19 antibody produced in rabbit

affinity isolated antibody

• 同義詞: CK-19, Cytokeratin-19, K19, KRT19, Keratin type I cytoskeletal 19
• MDL號碼: MFCD02263565
• 分類程式碼代碼: 12352203
• NACRES: NA.41

屬性

• 生物源: rabbit
• 共軛: unconjugated
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: antigen 44 kDa
• 物種活性: mouse, human, rat
• 濃度: ~1 mg/mL
• 技術: ELISA: 1:10000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI登錄號: P08727
• UniProt登錄號: P08727
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... KRT19(3880)

描述

一般說明

Anti-Keratin 19 Antibody detects endogenous levels of total Keratin 19 protein.

Cytokeratin 19 (KRT19) is a cytoplasmic intermediate filament protein with a α-helical central domain. It belongs to the acidic type I cytokeratin family of proteins (KRTs). This gene is mapped to human chromosome 17q21.

免疫原

The antiserum was produced against synthesized peptide derived from human Keratin 19.

Immunogen Range: 231-280

生化／生理作用

Cytokeratin 19 (KRT19) plays a major role in structural rigidity and multipurpose scaffolds. Overexpression of this gene in various cancers may participate in tumorigenic transformation. It may modulate signaling pathways and mediate cell apoptosis, cell cycle arrest, invasion and metastasis. KRT19 plays a vital role in the cancer stemness of hepatocellular carcinoma (HCC).

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: nwg
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable