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Merck
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Key Documents

SAB4501661

Sigma-Aldrich

Anti-RHOA antibody produced in rabbit

affinity isolated antibody

同義詞:

ARH12, ARHA, ARHA2, H12, RHO12

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen 21 kDa

物種活性

rat, mouse, human

濃度

~1 mg/mL

技術

ELISA: 1:1000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... RHOA(387)

一般說明

Anti-RHOA Antibody detects endogenous levels of total RHOA protein.
RhoA (ras homolog family member A) belongs to the Rho GTPase family of proteins. It is located on human chromosome 3p21.31.

免疫原

The antiserum was produced against synthesized peptide derived from human RhoA.

Immunogen Range: 144-193

生化/生理作用

In multiciliated epithelial cells, RhoA (ras homolog family member A) controls the actin network dynamics. It also modulates membrane protrusion and contractility in the cell body. RhoA is one of the essential factor for Ras transformation. It is associated with cancer metastasis.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

GPX1 (Glutathione Peroxidase 1)
Kulak MV and Weigel RJ
Atlas of Genetics and Cytogenetics in Oncology and Haematology (2014)
Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation
Khosravi-Far R, et al.
Molecular and Cellular Biology, 15(11), 6443-6453 (1995)
Variegated RHOA mutations in human cancers
Kataoka K and Ogawa S
Experimental Hematology, 44(12), 1123-1129 (2016)
Spatiotemporal dynamics of RhoA activity in migrating cells
Pertz O, et al.
Nature, 440(7087), 1069-1072 (2006)
RhoA regulates actin network dynamics during apical surface emergence in multiciliated epithelial cells
Sedzinski J, et al.
Journal of Cell Science, 130(2), 420-428 (2017)

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