推薦產品
生物源
rabbit
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
antigen 53 kDa
物種活性
human, mouse
濃度
~1 mg/mL
技術
ELISA: 1:5000
immunofluorescence: 1:100-1:500
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... GLP1R(2740)
一般說明
抗-GLP1R抗体可检测总GLP1R蛋白的内源性水平。
胰高血糖素样肽1受体(GLP1R)蛋白属于B类G蛋白偶联受体(GPCR)分泌素家族。这一经典七重跨膜蛋白在心血管系统中大量表达。GLP1R基因位于人染色体6p21上。抗GLP1R抗体检测总GLP1R蛋白的内源性水平。
免疫原
该抗血清是针对衍生自人GLP1R的合成肽而生成的。
免疫原范围： 101-150
免疫原范围： 101-150
應用
兔抗GLP1R抗体可用于免疫组织化学染色分析。
生化／生理作用
胰高血糖素样肽1受体(GLP1R)蛋白参与蛋白激酶A (PKA)、磷脂酰肌醇3-激酶(PI3K)、MEK1/2和内皮型一氧化氮合酶(eNOS)通路的激活。因此，它在减少细胞凋亡、改善能量代谢、减轻心肌细胞炎症、舒张心肌动脉血管等方面发挥关键作用。GLP1R的N端胞外结构域参与配体结合。GLP1R基因的改变可能增加冠心病(CAD)的风险。
特點和優勢
完放心地使用我们的抗体。如果抗体在您的申请的研究中不起作用，我们将全额退款或安排替代抗体。了解更多信息。
外觀
兔IgG，溶于磷酸盐缓冲液（不含Mg2+和Ca2+），pH 7.4,150mM NaCl，0.02％叠氮化钠和50％甘油中。
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
未找到適合的產品？
試用我們的產品選擇工具.
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
nwg
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Xiaowei Ma et al.
Journal of diabetes research, 2018, 1054192-1054192 (2018-10-03)
Glucagon-like peptide 1 (GLP-1) bestows protective effects upon the cardiovascular system through direct cardiovascular interactions or by improvements to metabolic function. Both these effects are thought to be at least partly mediated by the GLP-1 receptor (GLP-1R). This case-controlled study
Sama Abdulmalik et al.
Differentiation; research in biological diversity, 120, 1-9 (2021-06-02)
Tendon injuries are common and account for up to 50% of musculoskeletal injuries in the United States. The poor healing nature of the tendon is attributed to poor vascularization and cellular composition. In the absence of FDA-approved growth factors for
Qian Zhang et al.
BMC complementary and alternative medicine, 14, 188-188 (2014-06-11)
Berberine is known to improve glucose and lipid metabolism disorders, but it poorly absorbed into the blood stream from the gut. Therefore, the exact underlying mechanism for berberine is still unknown. In this study, we investigated the effect of berberine
Yichao Fan et al.
Molecular vision, 20, 1557-1568 (2014-12-10)
Exendin-4 (E4), a long-acting agonist of the hormone glucagon-like peptide 1 receptor (GLP-1R), is administered to treat type II diabetes in the clinical setting and also shows a neuroprotective effect. Our previous studies demonstrated its protective effect in early experimental
Sze Wa Chan et al.
Neuropharmacology, 83, 71-78 (2014-04-15)
The use of glucagon-like peptide-1 (7-36) amide (GLP-1) receptor agonists for the treatment of type 2 diabetes mellitus is commonly associated with nausea and vomiting. Previous studies using Suncus murinus revealed that the GLP-1 receptor agonist, exendin-4, induces emesis via
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務