SAB4200197
Anti-Periostin antibody,Mouse monoclonal
clone 47, purified from hybridoma cell culture
同義詞:
Periostin Antibody, Periostin Antibody - Monoclonal Anti-Periostin antibody produced in mouse, Anti-OSF2, Anti-Osteoblast specific factor 2, Anti-PDLPOSTN, Anti-POSTN
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About This Item
分類程式碼代碼:
12352203
NACRES:
NA.41
推薦產品
生物源
mouse
共軛
unconjugated
抗體表格
purified from hybridoma cell culture
抗體產品種類
primary antibodies
無性繁殖
47, monoclonal
形狀
buffered aqueous solution
分子量
antigen ~88 kDa
物種活性
human
濃度
~1.0 mg/mL
技術
western blot: 2-4 μg/mL using whole extracts of HEK-293T cells over expressing human Periostin
同型
IgG1
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... POSTN(10631)
一般說明
Periostin (POSTN) is also known as osteoblast-specific factor-2. It is a 90 kDa protein expressed in the extracellular matrix and bones. POSTN is an adhesive glycoprotein. The gene encoding this protein is localized on human chromosome 13q13.3.
免疫原
human Periostin recombinant protein. The human protein shares 87% homology with the mouse protein.
應用
Monoclonal Anti-Periostin antibody produced in mouse has been used to develop a periostin imaging PET probe.
生化/生理作用
Periostin (POSTN) has a role in the differentiation and cell adhesion of osteogenic cells. It functions as a biomarker of T-helper cells type 2-mediated inflammatory diseases. The protein has been associated with various cancers. POSTN is involved in epithelial-mesenchymal transition and extracellular matrix degradation.
外觀
0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
閃點(°F)
Not applicable
閃點(°C)
Not applicable
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Epithelial periostin expression is correlated with poor survival in patients with invasive breast carcinoma.
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PLoS ONE, 12(11), e0187635-e0187635 (2017)
Functional role of periostin in development and wound repair: implications for connective tissue disease.
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Mechanism of Periostin Production in Human Bronchial Smooth Muscle Cells.
Makita K, et al.
International Archives of Allergy and Immunology, 175(1-2), 26-35 (2018)
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