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Key Documents

SAB4100313

Sigma-Aldrich

Monoclonal Anti-LGALS3BP antibody produced in mouse

clone LGALS3BP-A265, culture supernatant

同義詞:

Anti-90K, Anti-BTBD17B, Anti-Lectin, galactoside-binding, soluble, 3 binding protein, Anti-MAC-2-BP

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

共軛

unconjugated

抗體表格

culture supernatant

抗體產品種類

primary antibodies

無性繁殖

LGALS3BP-A265, monoclonal

形狀

aqueous solution

分子量

antigen predicted mol wt 65.2 kDa

物種活性

human

技術

western blot: suitable

同型

IgG1

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... LGALS3BP(3959)

一般說明

Lectin galactoside-binding soluble 3 binding protein (LGALS3BP), a tumor-secreted antigen, is a large oligomeric and highly glycosylated protein. The LGALS3BP gene is located on human chromosome 17q25.

免疫原

LGALS3BP purified recombinant protein

生化/生理作用

Lectin galactoside-binding soluble 3 binding protein (LGALS3BP) also known as Mac-2 binding protein (M2BP) acts as a ligand of the lactose-specific S-type lectin, galectin-3. Mac-2 binding protein (M2BP) participates in cell adhesion and in tumor progression. Serum Mac-2 binding protein glycosylation isomer (M2BPGi) is considered as an important marker to study the criticality of liver disease.

外觀

Solution in Dulbecco′s Modified Eagle′s Medium with 10% fetal calf serum and 15 mM sodium azide.

免責聲明

Unless otherwise stated in our catalog, our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Enza Piccolo et al.
Journal of translational medicine, 13, 248-248 (2015-07-30)
A previous report has shown that LGALS3BP (also known as 90K or Mac-2 BP) has antitumor activity in colorectal cancer (CRC) via suppression of Wnt signalling with a novel mechanism of ISGylation-dependent ubiquitination of β-catenin. The role of LGALS3BP in

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