SAB1412143

ANTI-GUCY2D antibody produced in mouse

clone 7E5, purified immunoglobulin, buffered aqueous solution

• 同義詞: CORD5, CORD6, CYGD, GUC1A4, GUCY2D
• 分類程式碼代碼: 12352203
• NACRES: NA.41
• 共軛: unconjugated
• application: ELISA (i); IF; WB
• 無性繁殖: 7E5, monoclonal
• 物種活性: human
• 技術: indirect ELISA: suitable; indirect immunofluorescence: suitable; western blot: 1-5 μg/mL

屬性

• 生物源: mouse
• 品質等級: 100
• 共軛: unconjugated
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: 7E5, monoclonal
• 形狀: buffered aqueous solution
• 分子量: antigen 37.73 kDa
• 物種活性: human
• 技術: indirect ELISA: suitable; indirect immunofluorescence: suitable; western blot: 1-5 μg/mL
• 同型: IgG
• NCBI登錄號: NM_000180
• UniProt登錄號: Q02846
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... GUCY2D(3000)

描述

一般說明

This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases. (provided by RefSeq)

免疫原

GUCY2D (NP_000171, 521 a.a. ~ 630 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
RKVAQGSRSSLGARSMSDIRSGPSQHLDSPNIGVYEGDRVWLKKFPGDQHIAIRPATKTAFSKLQELRHENVALYLGLFLARGAEGPAALWEGNLAVVSEHCTRGSLQDL

外觀

Solution in phosphate buffered saline, pH 7.4

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable