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Merck
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Key Documents

SAB1300678

Sigma-Aldrich

Anti-KLF4 antibody produced in rabbit

saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution

同義詞:

Anti-EZF, Anti-GKLF, Anti-Kruppel-like factor 4

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

saturated ammonium sulfate (SAS) precipitated

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

物種活性

human

技術

indirect ELISA: 1:1000
western blot: 1:100-1:500

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... KLF4(9314)

一般說明

Krüppel-like factor 4 (KLF4) is a transcription factor. It can act both as a transcriptional activator or repressor. The gene encoding this protein is localized on human chromosome 9q31.2.

免疫原

KLF4 (NP_004226.3, )
This antibody is generated from rabbits immunized with a his tag recombinant protein of human KLF4.

生化/生理作用

Krüppel-like factor 4 (KLF4) is involved in cell growth, proliferation and differentiation in the colon. It is down-regulated in both mouse and human colonic adenomas. The protein has been implicated as a tumor suppressor in the gut, whereas in breast cancer, KLF4 is an oncogene. It is also involved in reprogramming differentiated cells into pluripotent stem cells.

外觀

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Dynamic down-regulation of Kruppel-like factor 4 in colorectal adenoma-carcinoma sequence.
Xu J
Journal of Cancer Research and Clinical Oncology (2008)
Kruppel-like factor 4 (KLF4): What we currently know.
Ghaleb AM and Yang VW
Gene (2017)
Kruppel-like factor 4 is acetylated by p300 and regulates gene transcription via modulation of histone acetylation.
Evans PM
The Journal of Biological Chemistry (2007)
KLF4 is a Novel Candidate Tumor Suppressor Gene in Pancreatic Ductal Carcinoma
Francesca Zammarchi
The American Journal of Pathology (2011)
Advances in Reprogramming Somatic Cells to Induced Pluripotent Stem Cells
Minal Patel
Stem Cell Reviews (2010)

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