推薦產品
化驗
≥98.0%
抗生素活性譜
Gram-negative bacteria
Gram-positive bacteria
mycoplasma
作用方式
DNA synthesis | interferes
SMILES 字串
CC(=O)NS(=O)(=O)c1ccc(N)cc1
InChI
1S/C8H10N2O3S/c1-6(11)10-14(12,13)8-4-2-7(9)3-5-8/h2-5H,9H2,1H3,(H,10,11)
InChI 密鑰
SKIVFJLNDNKQPD-UHFFFAOYSA-N
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一般說明
Chemical structure: sulfonamide
應用
Sulfacetamide is used to study the treatment of acne and seborrheic dermatitis. It is used to study neonatal chlamydial conjunctivitis and meningococcal conjunctivitis.
生化／生理作用
Sulfacetamide is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfacetamide is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid. It is active against Gram positive bacteria, Gram negative bacteria and Chlamydia. Mode of resistance is via the alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.
包裝
100G,500G
其他說明
Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place.Storage class (TRGS 510): Non Combustible Solids
訊號詞
Warning
危險聲明
危險分類
Skin Sens. 1 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 2
個人防護裝備
Eyeshields, Gloves, type N95 (US)
SODIUM SULFACETAMIDE FOR SEBORRHEIC DERMATITIS
STEPHEN T. WHELAN
American Journal of Diseases of Children, 71, 724-724 (1955)
Demet Sensoy et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 72(3), 487-495 (2009-02-19)
The aim of this study was to prepare bioadhesive sulfacetamide sodium (SA) microspheres to increase their residence time on the ocular surface and to enhance their treatment efficacy on ocular keratitis. Microspheres were fabricated by spray drying method using mixture
Rade Injac et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 25(4), 424-431 (2008-03-19)
A separation technique for zinc bacitracin, polymyxin B, oxytetracycline and sulfacetamide in animal feedstuffs by micellar electrokinetic capillary chromatography (MEKC) was developed. The running buffer was 20 mmol l(-1) borate, 20 mmol l(-1) phosphate, pH 8.4, containing 20 mmol l(-1)
E Kremer et al.
Journal of inorganic biochemistry, 100(7), 1167-1175 (2006-04-06)
The synthesis, characterization and comparative biological study of a series of antibacterial copper complexes with heterocyclic sulfonamides were reported. Two kinds of complexes were obtained with the stoichiometries [Cu(L)2] . H2O and [Cu(L)2(H2O)4] . nH2O. They were characterized by infrared
Fatmah A M Al-Omary et al.
Bioorganic & medicinal chemistry, 18(8), 2849-2863 (2010-03-31)
A new series of 2,6-substituted-quinazolin-4-ones was designed, synthesized, and evaluated for their in vitro DHFR inhibition, antimicrobial, and antitumor activities. Compounds 22, 33-37, 39-43, and 45 proved to be active DHFR inhibitors with IC(50) range of 0.4-1.0microM. Compound 18 showed
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