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Key Documents

S8751

Sigma-Aldrich

磺胺胍

同義詞:

4-氨基-N-(氨基亚氨基甲基)苯磺酰胺, 4-氨基-N-胍基苯磺酰胺

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About This Item

經驗公式(希爾表示法):
C7H10N4O2S
CAS號碼:
分子量::
214.24
Beilstein:
2695326
EC號碼:
MDL號碼:
分類程式碼代碼:
51283914
PubChem物質ID:
NACRES:
NA.85

生物源

synthetic (Organic)

形狀

powder

顏色

white to off-white

溶解度

1 M HCl: soluble 50 mg/mL

抗生素活性譜

Gram-negative bacteria
Gram-positive bacteria

作用方式

DNA synthesis | interferes
enzyme | inhibits

SMILES 字串

NC(=N)NS(=O)(=O)c1ccc(N)cc1

InChI

1S/C7H10N4O2S/c8-5-1-3-6(4-2-5)14(12,13)11-7(9)10/h1-4H,8H2,(H4,9,10,11)

InChI 密鑰

BRBKOPJOKNSWSG-UHFFFAOYSA-N

基因資訊

尋找類似的產品? 前往 產品比較指南

一般說明

化学结构:磺胺

應用

磺胺胍被用来阻止叶酸的合成。可用于研究其对微孢子生长和宿主细胞活力的影响

生化/生理作用

磺胺胍是一种磺胺类抗生素。磺酰胺可通过抑制二氢蝶呤合酶来阻止二氢叶酸的合成。磺胺类药物是细菌对氨基苯甲酸(PABA;细菌中叶酸合成所必需)的竞争性抑制剂。磺胺胍是一种二氢叶酸还原酶(DHFR)的抑制剂。磺胺类药物对革兰氏阳性细菌和革兰氏阴性细菌具有活性。抗性模式是通过二氢蝶呤合酶的改变或叶酸合成的替代途径。

其他說明

将容器密闭保存在干燥和通风良好的地方。在干燥处保存。储存类别 (TRGS 510):非易燃固体

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


分析證明 (COA)

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