S7826

SMER3

≥98% (HPLC)

• 同義詞: 9H-Indeno-[1,2-e]-[1,2,5]-oxadiazolo-[3,4-b]-pyrazin-9-one
• 經驗公式（希爾表示法）: C₁₁H₄N₄O₂
• CAS號碼: 67200-34-4
• 分子量：: 224.18
• MDL號碼: MFCD00451458
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329824591
• NACRES: NA.77

屬性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: yellow
• 溶解度: DMSO: ≥30 mg/mL
• 儲存溫度: 2-8°C
• SMILES 字串: O=C1c2ccccc2-c3nc4nonc4nc13
• InChI: 1S/C11H4N4O2/c16-9-6-4-2-1-3-5(6)7-8(9)13-11-10(12-7)14-17-15-11/h1-4H
• InChI 密鑰: SFSSAKVWCKFRHE-UHFFFAOYSA-N

描述

應用

SMER3 may be used in cell signaling studies.

生化／生理作用

Inhibition of SCF^Met30 by SMER3 blocks the ubiquitination of Met4 and activates the Met4-containing transcription complex. The induction of MET-genes results in cell cycle arrest and reduced cell proliferation.¹

Small molecule enhancer of rapamycin (SMER); specific inhibitor of Ubiquitin E3 ligase.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable