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About This Item
經驗公式（希爾表示法）:
C41H65N13O10
CAS號碼:
分子量：:
900.04
MDL號碼:
分類程式碼代碼:
12352209
PubChem物質ID:
NACRES:
NA.26
推薦產品
產品名稱
物质 P片段 1-7, ≥97% (HPLC)
品質等級
化驗
≥97% (HPLC)
形狀
powder
成份
Peptide content, ≥65%
顏色
white
UniProt登錄號
應用
cell analysis
儲存溫度
−20°C
SMILES 字串
NCCCCC(NC(=O)C1CCCN1C(=O)C(N)CCCNC(N)=N)C(=O)N2CCCC2C(=O)NC(CCC(N)=O)C(=O)NC(CCC(N)=O)C(=O)NC(Cc3ccccc3)C(O)=O
InChI
1S/C41H65N13O10/c42-19-5-4-12-28(51-37(60)30-13-7-21-53(30)38(61)25(43)11-6-20-48-41(46)47)39(62)54-22-8-14-31(54)36(59)50-27(16-18-33(45)56)34(57)49-26(15-17-32(44)55)35(58)52-29(40(63)64)23-24-9-2-1-3-10-24/h1-3,9-10,25-31H,4-8,11-23,42-43H2,(H2,44,55)(H2,45,56)(H,49,57)(H,50,59)(H,51,60)(H,52,58)(H,63,64)(H4,46,47,48)
InChI 密鑰
KPHDBQWTCKBKIL-UHFFFAOYSA-N
基因資訊
human ... TAC1(6863)
相關類別
Amino Acid Sequence
Arg-Pro-Lys-Pro-Gln-Gln-Phe
生化／生理作用
应用于孤束核时具有抑制和减缓心率作用的片段
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
Anna Carlsson et al.
European journal of pharmacology, 626(2-3), 250-255 (2009-10-20)
We have recently explored the role of the tachykinin substance P neuroactive fragment substance P(1-7) in the mediation of anti-inflammatory effects using a blister model in the rat paw (Wiktelius et al., 2006). We observed that this heptapeptide induced a
Qin Zhou et al.
Peptides, 32(8), 1661-1665 (2011-07-19)
The N-terminal substance P fragment SP(1-7) is known to modulate hyperalgesia and opioid withdrawal in animal models. This study examined the effects of intraperitoneal (i.p.) injections of SP(1-7) on chronic morphine tolerance and on the levels of dynorphin B (DYN
Milad Botros et al.
Peptides, 27(4), 753-759 (2005-10-12)
Endomorphin-1 (EM-1) and endomorphin-2 (EM-2) represent two opioid active tetrapeptides with high affinity and selectivity for the mu-opioid (MOP) receptor. Both EM-1 and EM-2 exhibit strong inhibition of pain signals in the central nervous system (CNS). In contrast to these
Qin Zhou et al.
Peptides, 25(11), 1951-1957 (2004-10-27)
The aminoterminal fragment of substance P (SP), SP(1-7), has been suggested to modulate the expression of opiate tolerance and withdrawal behaviors in rodents. However, the mechanism of this effect is not yet clarified. Using a rat model we have previously
Qin Zhou et al.
Neuroscience letters, 320(3), 117-120 (2002-02-20)
The biologically active substance P (SP) N-terminal metabolite SP(1-7) has been reported to modulate several neural processes such as learning, locomotor activity and reaction to opioid withdrawal. Although all these processes are believed to be associated with dopaminergic transmission no
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