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Merck
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Key Documents

S0802

Sigma-Aldrich

硬脂酰辅酶 A 锂盐

≥90%

同義詞:

十八烷酰基辅酶 A

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About This Item

經驗公式(希爾表示法):
C39H70N7O17P3S
CAS號碼:
分子量::
1034.00
分類程式碼代碼:
41106305
NACRES:
NA.51

品質等級

化驗

≥90%

儲存溫度

−20°C

應用

硬脂酰辅酶 A 锂盐可用作测定微粒体中硬脂酰辅酶去饱和酶的底物。
辅酶 A 作为酰基载体乙酰辅酶 A 发挥作用。脂酰辅酶 是参与多不饱和脂肪酸合成和PPAR信号通路的饱和脂肪酸代谢产物。硬脂酰辅酶A用于研究硬脂酰辅酶A去饱和酶的特异性和动力学,可导致形成单不饱和脂肪酸。

生化/生理作用

硬脂酰辅酶A是参与多不饱和脂肪酸合成和PPAR信号通路的饱和脂肪酸代谢产物。硬脂酰辅酶A是硬脂酰辅酶A去饱和酶的底物。硬脂酰辅酶A去饱和是不饱和脂肪酸生物合成的关键步骤。辅酶A硬脂酰辅酶A去饱和酶可将硬脂酰辅酶A转化为油酰辅酶A。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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R Ariel Igal
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As part of a shift toward macromolecule production to support continuous cell proliferation, cancer cells coordinate the activation of lipid biosynthesis and the signaling networks that stimulate this process. A ubiquitous metabolic event in cancer is the constitutive activation of
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Roongta UV, et al.
Molecular Cancer Research, 9(11), 1551-1561 (2011)
The biosynthesis of hepatic cholesterol esters and triglycerides is impaired in mice with a disruption of the gene for stearoyl-CoA desaturase 1
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The Journal of Biological Chemistry, 275(39), 30132-30138 (2000)
Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity
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Consumption of trans fatty acids is positively correlated with cardiovascular diseases and with atherogenic risk factors. Trans fatty acids might play their atherogenic effects through lipid metabolism alteration of vascular cells. Accumulation of lipids in vascular smooth muscle cells is

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