RAB0564

小鼠Tnfsf4 /肿瘤坏死因子配体超家族成员4 ELISA试剂盒

for serum, plasma and cell culture supernatants

• 分類程式碼代碼: 41116158
• NACRES: NA.84

屬性

• 物種活性: mouse
• 包裝: kit of 96 wells (12 strips x 8 wells)
• 技術: ELISA: suitable
• 輸入: sample type serum; sample type plasma; sample type cell culture supernatant(s)
• assay range: inter-assay cv: <10%; intra-assay cv: <12%; sensitivity: 30 pg/mL
• 檢測方法: colorimetric
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 基因資訊: mouse ... Tnfsf4(22164)

描述

一般說明

This ELISA antibody pair detects mouse TNFSF4/OX40.

應用

请参考Protocol了解详情。

生化／生理作用

Tumor necrosis factor (TNF) superfamily member 4 (Tnfsf4) signals specifically through the OX40 receptor, which is expressed primarily on CD4⁺T cells but also on certain activated CD8⁺T cells. Tnfsf4 acts as a costimulatory signal, which is essential for a productive interaction between antigen presenting cells and their target T-cells. It enhances cell proliferation and survival and increases expression of regulated on activation, normal T cell expressed and secreted (RANTES) or chemokine ligand 5 (CCL5), interleukins-2 and -3 and interferon γ (IFNg). Tnfsf4 signaling plays an important role in immuno-regulatory communication and immune-tolerance. Polymorphisms in the TNFSF4 gene leads to the development of autoimmune thyroid diseases (AITDs), rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and systemic sclerosis (SSc).

其他說明

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

套裝中的組件也可單獨購買

• RABTMB3 ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
• RABSTOP3 ELISA Stop Solution (Item I)
• RABELADA ELISA 1X Assay/Sample Diluent Buffer A (Item D1)
• RABELADB ELISA 5X Assay/Sample Diluent Buffer B (Item E1)
• RABWASH4 20X Wash Buffer (Item B)

安全資訊

• 象形圖: GHS05
• 訊號詞: Warning
• 危險聲明: H290
• 防範說明: P234 - P390
• 危險分類: Met. Corr. 1
• 儲存類別代碼: 8A - Combustible corrosive hazardous materials
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable