推薦產品
物種活性
mouse
包裝
kit of 96 wells (12 strips x 8 wells)
技術
ELISA: suitable
capture ELISA: suitable
輸入
sample type cell lysate
sample type tissue lysate
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 2 pg/mL
standard curve range: 4.1-1000 pg/mL
檢測方法
colorimetric
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
mouse ... Vegfa(22339)
一般說明
The Mouse VEGF ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of mouse VEGF cell lysate and tissue lysate.
免疫原
Recombinant Mouse VEGF-A
應用
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Mouse VEGF ELISA Kit has been used to determine the concentration of VEGF expression in samples using ELISA.
生化／生理作用
Vascular endothelial growth factor (VEGF) is a critical factor in regulating angiogenesis in both physiological and pathological conditions. Transforming growth factor-α (TGF-α), TGF-β and platelet derived growth factor can potentially activate VEGF activity. VEGF mediates its activity through tyrosine kinase receptors, vascular endothelial growth factor receptor-1 (VEGFR-1) and VEGFR-2. VEGF produced by tumour cells and macrophages, plays a key role in cancer development by promoting endothelial cells proliferation and increasing vascular permeability. Enhanced expression of VEGF plays a key role in urologic neoplasm like bladder cancer, renal cell carcinoma, and cervical cancer. Polymorphism in VEGF gene increases the disease susceptibility. Blocking of VEGF mediated signalling pathway is a potential therapeutic strategy for cancer patients.
其他說明
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
套裝中的組件也可單獨購買
產品號碼
描述
SDS
訊號詞
Warning
危險聲明
防範說明
危險分類
Met. Corr. 1
儲存類別代碼
8B - Non-combustible corrosive hazardous materials
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Parthenolide inhibits tumor-promoting effects of nicotine in lung cancer by inducing P53-dependent apoptosis and inhibiting VEGF expression
Talib WH, et al.
Biomedicine and Pharmacotherapy, 107, 1488-1495 (2018)
Stimulation of angiogenesis using single-pulse low-pressure shock wave treatment
Sundaram S, et al.
Journal of Molecular Medicine, 96(11), 1177-1187 (2018)
Combination of metformin and curcumin targets breast cancer in mice by angiogenesis inhibition, immune system modulation and induction of p53 independent apoptosis
Falah RR, et al.
Therapeutic Advances in Medical Oncology, 9(4), 235-252 (2017)
Fu-Li Xiang et al.
Circulation. Heart failure, 7(5), 831-842 (2014-08-12)
The adult epicardium is a potential source of cardiac progenitors after myocardial infarction (MI). We tested the hypothesis that cardiomyocyte-specific overexpression of membrane-associated human stem cell factor (hSCF) enhances epicardial activation, epicardium-derived cells (EPDCs) production, and myocardial arteriogenesis post MI.
Relationship of common vascular endothelial growth factor polymorphisms and haplotypes with the risk of cervical cancer in Tunisians
Zidi S, et al.
Cytokine, 74(1), 108-112 (2015)
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