推薦產品
物種活性
human
包裝
kit of 96 wells (12 strips x 8 wells)
技術
ELISA: suitable
capture ELISA: suitable
輸入
sample type serum
sample type cell culture supernatant(s)
sample type urine
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 45 pg/mL
standard curve range: 46.88-3000 pg/mL
檢測方法
colorimetric
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
human ... BMP2(650)
一般說明
BMP2（骨形态发生蛋白2）由位于人染色体20p12.3上的基因编码。 编码的蛋白质属于转化生长因子-β （TGFβ）超家族。BMP-2表达于心脏、肺和背主动脉中。
人 BMP2（骨形态发生蛋白2） ELISA（酶联免疫吸附测定）试剂盒采用体外酶联免疫吸附测定法，定量测定人血清、血浆、细胞培养物上清液和尿液中的BMP-2含量。
免疫原
重组人 BMP2
應用
仅供研究使用。不用于诊断操作。
人BMP2（骨形态发生蛋白2） ELISA试剂盒已被用于测量小鼠类器官条件培养基中BMP的浓度。
请参阅随附的常规ELISA试剂盒 操作步骤 （夹心、竞争性&和间接ELISA）
人BMP2（骨形态发生蛋白2） ELISA试剂盒已被用于测量小鼠类器官条件培养基中BMP的浓度。
请参阅随附的常规ELISA试剂盒 操作步骤 （夹心、竞争性&和间接ELISA）
生化／生理作用
BMP2（骨形态发生蛋白2）在自主神经系统谱系特异性碱性-螺旋-环-螺旋蛋白MASH1（哺乳动物无刚毛鳞甲同系物-1）的激活以及神经嵴干细胞的体外自主神经发生中具有至关重要的作用。在骨修复过程中，BMP-2控制Runt相关转录因子2（Runx2）和Osterix（Osx）的表达，从而增强间充质干细胞的迁移、增殖和成骨分化。 除了具有成骨活性外，BMP-2在心脏形态发生中也具有重要作用。重组人骨形态发生蛋白2（rhBMP-2）在口腔鳞状细胞癌的发病机理中具有至关重要的作用。BMP-2基因突变与骨质疏松症有关。
其他說明
本产品提供样本分析证书。
请在批号对应的文本框中输入单词 sample 。
请在批号对应的文本框中输入单词 sample 。
訊號詞
Warning
危險聲明
防範說明
危險分類
Met. Corr. 1
儲存類別代碼
8A - Combustible corrosive hazardous materials
客戶也查看了
Tobias Sinnberg et al.
Biology open, 7(6) (2018-05-03)
Despite recent progress in melanoma therapy via inhibition of activated oncogenes or immune stimulation, most stage IV melanoma patients still have limited survival times. Existing therapeutic approaches eventually fail to prevent further invasion and metastasis, which is driven by a
Khaled Waleed Zaid et al.
Asian Pacific journal of cancer prevention : APJCP, 17(3), 927-932 (2016-04-05)
Bone morphogenetic proteins (BMPs), belonging to the transforming growth factor-β superfamily, regulate many cellular activities including cell migration, differentiation, adhesion, proliferation and apoptosis. Use of recombinant human bone morphogenic protein?2 (rhBMP?2) in oral and maxillofacial surgery has seen a tremendous
Yingnan Geng et al.
Communications biology, 4(1), 82-82 (2021-01-21)
Bone has a remarkable potential for self-healing and repair, yet several injury types are non-healing even after surgical or non-surgical treatment. Regenerative therapies that induce bone repair or improve the rate of recovery are being intensely investigated. Here, we probed
Katarina Dathe et al.
American journal of human genetics, 84(4), 483-492 (2009-03-31)
Autosomal-dominant brachydactyly type A2 (BDA2), a limb malformation characterized by hypoplastic middle phalanges of the second and fifth fingers, has been shown to be due to mutations in the Bone morphogenetic protein receptor 1B (BMPR1B) or in its ligand Growth
Agnieszka Smieszek et al.
Journal of clinical medicine, 7(12) (2018-11-30)
Metformin, the gold standard in type 2 diabetes treatment, is a drug with multi-faceted effects. Currently, metformin has gained much attention as an agent that may find application in regenerative medicine. In this study, we considered its pro-osteogenic function in
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務