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Merck
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重要文件

R0656

Sigma-Aldrich

Anti-Rab14 (C-terminal) antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution

同義詞:

Anti-F protein-binding protein 1, Anti-GTPase Rab14, Anti-RAB14, member RAS oncogene family, Anti-Small GTP binding protein RAB14

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen ~24 kDa

物種活性

mouse, human, rat

濃度

~1.0 mg/mL

技術

immunoprecipitation (IP): 5-10 μg using whole extract of human Raji cells
indirect immunofluorescence: 2.5-5 μg/mL using rat NRK cells fixed and permeabilized with 4% paraformaldehyde followed by 0.4% saponin
western blot: 1-2 μg/mL using whole extract of mouse brain

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... RAB14(51552)
mouse ... Rab14(68365)
rat ... Rab14(94197)

一般說明

Rab14 (Ras-related protein) is a Golgi-related Rab, that is located on chromosome 9q33.2. It is present in the endo-lysosomal pathway and contractile vacuole system of membranes. It is expressed almost in all tissues.
Rab14 (Ras-related protein) is a member of the Rab family of small guanosine triphosphatases (GTPases).

應用

Anti-Rab14 (C-terminal) antibody produced in rabbit has been used in:immunoblotting, immunoprecipitation, indirect immunofluorescence.

生化/生理作用

Rab14 (Ras-related protein) participates in membrane trafficking between the Golgi complex and endosomes. It may play an important role in surfactant secretion.

外觀

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


分析證明 (COA)

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存取文件庫

The functions of Rab GTPases in plant membrane traffic
Woollard AAD and Moore I
Current Opinion in Plant Biology, 11(6), 610-619 (2008)
Annexin A2 interactions with Rab14 in alveolar type II cells
Gou D, et al.
The Journal of Biological Chemistry, 283(19), 13156-13164 (2008)
RabD, a Dictyostelium Rab14-related GTPase, regulates phagocytosis and homotypic phagosome and lysosome fusion
Harris E and Cardelli J
Journal of Cell Science, 115(Pt 18), 3703-3713 (2002)
A large-scale rheumatoid arthritis genetic study identifies association at chromosome 9q33.2
Chang M, et al.
PLoS Genetics, 4(6) (2008)
A Lacoma et al.
Virulence, 8(8), 1761-1775 (2017-08-02)
Staphylococcus aureus is a particularly difficult pathogen to eradicate from the respiratory tract. Previous studies have highlighted the intracellular capacity of S.aureus in several phagocytic and non-phagocytic cells. The aim of this study was to define S.aureus interaction within a

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