PZ0015

Trovafloxacin mesylate

>98% (HPLC), powder, Pannexin 1 inhibitor

• 同義詞: (1α,5α,6α)-7-(6-Amino-3-azabicyclo[3.1.0]hex-3-yl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid methanesulfonate, CP-99219-27, Trovafloxacin methanesulfonate
• 經驗公式（希爾表示法）: C₂₀H₁₅F₃N₄O₃ · CH₃SO₃H
• CAS號碼: 147059-75-4
• 分子量：: 512.46
• MDL號碼: MFCD00913361
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329823684
• NACRES: NA.77

屬性

• 產品名稱: Trovafloxacin mesylate, >98% (HPLC)
• 化驗: >98% (HPLC)
• 形狀: powder
• 顏色: white to off-white
• 溶解度: DMSO: >10 mg/mL
• 儲存溫度: room temp
• SMILES 字串: CS(O)(=O)=O.NC1C2CN(CC12)c3nc4N(C=C(C(O)=O)C(=O)c4cc3F)c5ccc(F)cc5F
• InChI: 1S/C20H15F3N4O3.CH4O3S/c21-8-1-2-15(13(22)3-8)27-7-12(20(29)30)17(28)9-4-14(23)19(25-18(9)27)26-5-10-11(6-26)16(10)24;1-5(2,3)4/h1-4,7,10-11,16H,5-6,24H2,(H,29,30);1H3,(H,2,3,4)/t10-,11+,16+;
• InChI 密鑰: DYNZICQDCVYXFW-AHZSKCOESA-N

描述

應用

Trovafloxacin mesylate has been used as a test compound in toxicity assay to assess its toxicity in 2D hepatocyte cultures. It has also been used to manipulate the mechanism of apoptotic cell disassembly during apoptosis.

生化／生理作用

Trovafloxacin mesylate acts as a pannexin1 (Panx1) inhibitor.

Trovafloxacin mesylate is a broad spectrum antibiotic.

Trovafloxacin mesylate is a broad spectrum antibiotic. Trovafloxacin mesylate blocks the activity of DNA gyrase and topoisomerase IV, enzymes essential in the repliction, transcription, and repair of bacterial DNA.

安全資訊

• 象形圖: GHS08,GHS05
• 訊號詞: Danger
• 危險聲明: H314,H361
• 防範說明: P202 - P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• 危險分類: Repr. 2 - Skin Corr. 1B
• 儲存類別代碼: 8A - Combustible corrosive hazardous materials
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable