1670207

Tolcapone

United States Pharmacopeia (USP) Reference Standard

• 同義詞: 3,4-Dihydroxy-4′-methyl-5-nitrobenzophenone, Ro 40-7592
• 經驗公式（希爾表示法）: C₁₄H₁₁NO₅
• CAS號碼: 134308-13-7
• 分子量：: 273.24
• MDL號碼: MFCD00866569
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329751344
• NACRES: NA.24

屬性

• 等級: pharmaceutical primary standard
• API 家族: tolcapone
• 製造商／商標名: USP
• 應用: pharmaceutical (small molecule)
• 格式: neat
• SMILES 字串: Cc1ccc(cc1)C(=O)c2cc(O)c(O)c(c2)[N+]([O-])=O
• InChI: 1S/C14H11NO5/c1-8-2-4-9(5-3-8)13(17)10-6-11(15(19)20)14(18)12(16)7-10/h2-7,16,18H,1H3
• InChI 密鑰: MIQPIUSUKVNLNT-UHFFFAOYSA-N
• 基因資訊: human ... COMT(1312)

描述

一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Tolcapone USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Tolcapone Tablets

生化／生理作用

Tolcapone is an orally active catechol-O-methyltransferase (COMT) inhibitor. It inhibits both central and peripheral COMT. Tolcapone crosses the blood-brain barrier, and has been used for L-DOPA adjunct therapy in the treatment of Parkinson′s Disease.

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他說明

Sales restrictions may apply.

安全資訊

• 象形圖: GHS09
• 訊號詞: Warning
• 危險聲明: H400
• 防範說明: P273 - P391 - P501
• 危險分類: Aquatic Acute 1
• 儲存類別代碼: 11 - Combustible Solids
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable