PLA0251
Rabbit anti-MEKK1 Antibody, Affinity Purified
Powered by Bethyl Laboratories, Inc.
同義詞:
E3 ubiquitin protein ligase, MAP/ERK kinase kinase 1, MAPK/ERK kinase kinase 1, MAPKKK1, MEK kinase 1, MEKK, MEKK 1, MEKK1, SRXY6, mitogen-activated protein kinase kinase kinase 1
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About This Item
分類程式碼代碼:
12352203
NACRES:
NA.41
推薦產品
生物源
rabbit
品質等級
抗體表格
affinity purified immunoglobulin
抗體產品種類
primary antibodies
等級
Powered by Bethyl Laboratories, Inc.
物種活性
human
技術
immunoprecipitation (IP): 5- 10 μg/mg
western blot: 1:2,000- 1:10,000
登錄號
NP_005912.1
運輸包裝
wet ice
儲存溫度
2-8°C
目標翻譯後修改
unmodified
基因資訊
rabbit ... MEKK1(4214)
免疫原
The epitope recognized by PLA0251 maps to a region between residue 50 and 100 of human MAP/ERK kinase kinase 1 using the numbering given in entry NP_005912.1 (GeneID 4214).
外觀
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
其他說明
MEK (MAPK/ERK kinase) kinase 1 (MEKK1) is encoded by the MAP3K1 (mitogen-activated protein kinase kinase kinase 1) gene. MEKK1 is a component of a protein kinase signal transduction cascade that activates the ERK and JNK kinase pathways by phosphorylation of MEK1 (MAP2K1) and MEK4 (MAP2K4). MEKK1 activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q13233].
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
nwg
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Qi Zhang et al.
The Journal of urology, 191(6), 1880-1888 (2014-01-18)
Mutations in the FLCN gene are responsible for fibrofolliculoma, pulmonary and renal cysts, and renal cell carcinoma in patients with Birt-Hogg-Dubé syndrome. To explore therapeutic approaches to renal cell carcinoma in patients with Birt-Hogg-Dubé syndrome we investigated the anticancer effects
Sun-Young Lee et al.
International journal of oncology, 45(2), 675-682 (2014-05-29)
Nutlin-3 which occupies the p53 binding pocket in HDM2, has been reported to activate apoptosis through both the transcriptional activity-dependent and -independent programs of p53. Transcription-independent apoptosis by nutlin-3 is triggered by p53 which is translocated to mitochondria. However, we
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