PLA0106
Rabbit anti-MSH2 Antibody, Affinity Purified
Powered by Bethyl Laboratories, Inc.
同義詞:
COCA1, FCC1, HNPCC, HNPCC1, LCFS2, MutS protein homolog 2, colon cancer, hMSH2, mutS (E. coli) homolog 2 (colon cancer; nonpolyposis type 1), mutS homolog 2, nonpolyposis type 1, nonpolyposis type 1 (E. coli)
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About This Item
推薦產品
生物源
rabbit
品質等級
抗體表格
affinity purified immunoglobulin
抗體產品種類
primary antibodies
等級
Powered by Bethyl Laboratories, Inc.
物種活性
mouse, human
技術
immunoprecipitation (IP): 2-10 μg/mg
western blot: 1:1,000-1:5,000
登錄號
P43246
UniProt登錄號
運輸包裝
wet ice
儲存溫度
2-8°C
目標翻譯後修改
unmodified
基因資訊
rabbit ... MSH2(4436)
免疫原
The epitope recognized by PLA0106 maps to a region between residues 1 and 50 of human mutS homolog 2 using the numbering given in Swiss-Prot entry P43246 (GeneID 4436).
外觀
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide
其他說明
MSH2 is an integral component of the DNA mismatch repair (MMR) system that functions to recognize aberrant structures and signals for the repair of single base mismatches or loops in replicated DNA. MSH2 has also been demonstrated to function as an anti-recombinase and may play a role in negatively regulating DNA repair. MSH2 can heterodimerize with MSH3 or MSH6. Mutations in MSH2 are linked to hereditary nonpolyposis colon cancer (HNPCC).
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類(WGK)
nwg
閃點(°F)
Not applicable
閃點(°C)
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
Human pathology, 45(6), 1258-1268 (2014-04-29)
ARID1A/BAF250a has been recently implicated as a tumor suppressor in gastric cancer. We sought to clarify the clinical significance of BAF250a/ARID1A in relation to other clinical parameters and relevant biomarkers in gastric carcinoma. Cases from 2 separate cohorts of patients
Molecular medicine reports, 10(2), 1003-1006 (2014-05-27)
Knowledge of the molecular biology of primary colorectal cancer (CRC) has improved in recent years, and one reason for this is the identification of microsatellite instability (MSI), which occurs in up to 15% of sporadic CRC. However, less is known
Anticancer research, 34(6), 3211-3215 (2014-06-13)
To assess the feasibility of Microsatellite Instability (MSI) analysis in uterine cavity washings for detecting endometrial cancer in Lynch syndrome. This was a proof-of-concept study in Lynch syndrome patients, scheduled for hysterectomy. At the beginning of surgical procedure, uterine cavity
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