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重要文件

P9544

Sigma-Aldrich

磷酸葡萄糖异构酶 来源于兔肌肉

Type XI, lyophilized powder, ≥200 units/mg protein

同義詞:

D-葡萄糖-6-磷酸酮醇异构酶, PGI, 磷酸糖变位酶

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About This Item

CAS號碼:
酶委員會編號:
EC號碼:
MDL號碼:
分類程式碼代碼:
12352204
NACRES:
NA.54

生物源

rabbit muscle

品質等級

種類

Type XI

形狀

lyophilized powder

比活性

≥200 units/mg protein

成份

protein, 70-100% biuret

儲存溫度

−20°C

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應用

磷酸葡萄糖异构酶(PGI)是在糖酵解的第二步中对D-葡萄糖-6-磷酸和D-果糖-6-磷酸的相互转化具有重要作用的一种酶。PGI负责糖酵解的第二步并参与到了葡萄糖的生成。它在细菌和真核生物中高度保守。它可用于将果糖转化为葡萄糖的糖测定中。产品9544属于XI型并来自于兔肌肉。它可用于需要低硫酸盐的酶系统中。

生化/生理作用

磷酸葡萄糖异构酶是一种异构酶、神经白细胞介素、自分泌运动因子以及分化和成熟的中介体。它负责碳的光合作用还原。

單位定義

一个酶活性单位是指在pH 7.4、温度25 °C条件下,每分钟将1.0 μm的D-果糖-6-磷酸转化为D-葡萄糖-6-磷酸所需的酶量。

外觀

含柠檬酸盐缓冲盐但基本无硫酸盐的粉末

象形圖

Health hazard

訊號詞

Danger

危險聲明

防範說明

危險分類

Resp. Sens. 1

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves


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分析證明 (COA)

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B K Campbell et al.
Reproduction (Cambridge, England), 140(5), 721-732 (2010-08-19)
Glucose is a critical metabolic fuel in most mammals although many foodstuffs also contain high levels of the monosaccharides, galactose and fructose. The aims of this work were to determine the insulin response to challenges of these sugars (experiment 1)
C J Jeffery et al.
Biochemistry, 39(5), 955-964 (2000-02-02)
The multifunctional protein phosphoglucose isomerase, also known as neuroleukin, autocrine motility factor, and differentiation and maturation mediator, has different roles inside and outside the cell. In the cytoplasm, it catalyzes the second step in glycolysis. Outside the cell, it serves
Veera Kainulainen et al.
Journal of bacteriology, 194(10), 2509-2519 (2012-03-06)
Glutamine synthetase (GS) and glucose-6-phosphate isomerase (GPI) were identified as novel adhesive moonlighting proteins of Lactobacillus crispatus ST1. Both proteins were bound onto the bacterial surface at acidic pHs, whereas a suspension of the cells to pH 8 caused their
Simone Frédérique Brenière et al.
PLoS neglected tropical diseases, 6(5), e1650-e1650 (2012-06-12)
The current persistence of Triatoma infestans (one of the main vectors of Chagas disease) in some domestic areas could be related to re-colonization by wild populations which are increasingly reported. However, the infection rate and the genetic characterization of the
Mohammad Amraei et al.
FEBS letters, 525(1-3), 151-155 (2002-08-07)
Phosphoglucose isomerase (PGI) is a cytosolic glycolytic enzyme that also functions as an extracellular cytokine (neuroleukin/autocrine motility factor (AMF)/maturation factor). Contrary to mammalian PGI, bacterial PGI was not internalized by the PGI/AMF receptor (gp78/AMF-R) and neither bacterial nor yeast PGI

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