推薦產品
生物源
human
品質等級
重組細胞
expressed in E. coli
化驗
≥90% (SDS-PAGE)
形狀
buffered aqueous glycerol solution
UniProt登錄號
應用
genomic analysis
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
human ... TP53(7157)
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一般說明
p53 is regulated by MDM2, which acts as a negative regulator of p53 transcription by promoting its degradation by functioning as an E3 ubiquitin ligase which recognizes the N′ terminal transactivation domain.
應用
可用于研究 p53 的翻译后修饰或蛋白质-蛋白质相互作用研究。
生化／生理作用
p53基因高度保守，在正常组织中表达。它是人类癌症中最常见的突变基因，研究人员已经描述了各种类型的恶性肿瘤、血液肿瘤和实体肿瘤中的500 多个基因突变。完整的 p53 功能对于维持细胞的非致瘤性表型至关重要。因此， p53在抑制癌症的发展中起着至关重要的作用。。
物理性質
GST-tagged, full-length human p53
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
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