推薦產品
品質等級
化驗
≥98% (HPLC)
形狀
solid
顏色
white to beige
溶解度
DMSO: soluble >10 mg/mL
H2O: insoluble
SMILES 字串
C1Sc2ccccc2-c3[nH]c4ccccc4c13
InChI
1S/C15H11NS/c1-3-7-13-10(5-1)12-9-17-14-8-4-2-6-11(14)15(12)16-13/h1-8,16H,9H2
InChI 密鑰
ZGOOPZVQMLHPFM-UHFFFAOYSA-N
基因資訊
human ... ALOX15(246)
mouse ... ALOX15(11687)
rat ... ALOX15(81639)
應用
PD 146176已被用于研究其对脂肪组织中离体白细胞三烯B4（LTB4）和脂氧素A4（LXA4）分泌的影响。
生化／生理作用
PD 146176通过抑制5-脂氧合酶1（15-LOX-1）来阻断神经保护素D1（NPD1）和类花生酸的合成。
15-脂氧合酶抑制剂
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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