推薦產品
品質等級
化驗
≥95% (HPLC)
形狀
powder
技術
HPLC: suitable
顏色
white to off-white
儲存溫度
−20°C
SMILES 字串
CC(N1)=NC=C(C[N+]2=CSC(CCO)=C2C)C1=O.Cl.[Cl-]
InChI
1S/C12H16N3O2S.2ClH/c1-8-11(3-4-16)18-7-15(8)6-10-5-13-9(2)14-12(10)17;;/h5,7,16H,3-4,6H2,1-2H3,(H,13,14,17);2*1H
InChI 密鑰
QHUYPZVMEJLSEB-UHFFFAOYSA-N
一般說明
羟基硫胺素是一种硫胺素抗代谢物，其饮食来源是通过摄入富含硫胺素的酸性食品。
應用
羟基硫胺素盐酸盐适用于：
- 作为参考标准品用于生成液相色谱-串联质谱（LC-MS/MS）的校准曲线定量测定红细胞中的羟基硫胺素焦磷酸盐 (OTPP)
- 作为人乳腺上皮细胞 (HMEC) 和乳腺癌细胞系中的硫胺素运输抑制剂
- 合成羟基硫胺素H苦酮酸盐
生化／生理作用
羟基硫胺素（OT）是一种硫胺素拮抗剂。它是一种转酮醇酶抑制剂，用于研究抗转移机制，尤其是涉及金属蛋白酶（MMP）的机制。它可以显著提高人肝癌细胞（HCC）对索拉非尼的敏感性，从而有利于肿瘤抑制。
羟乙胺抑制转酮醇酶，即控制戊糖磷酸途径非氧化分支的酶。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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文章
Neoplastic cells are highly dependent on the de novo synthesis of nucleotides to maintain sufficient pools to support DNA replication and the production of RNA.
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
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