重組細胞
expressed in E. coli
品質等級
化驗
≥90% (SDS-PAGE)
形狀
lyophilized powder
比活性
≥100 units/mL
分子量
monomer 24000
環保替代產品特色
Waste Prevention
Safer Solvents and Auxiliaries
Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
UniProt登錄號
環保替代類別
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
Escherichia coli K12 ... nfsB(945483)
相關類別
一般說明
硝基还原酶是一种黄素蛋白，由NfsB基因编码。它包含一个二聚体，每个亚基具有217个氨基酸和活性位点。该结构具有FMN和与酶结合的底物。
應用
大肠杆菌来源硝基还原酶可结合猪肝酯酶(PLE)用于偶联结合反应。它还还可结合探针HyCL-3和HyCL-4-AM针对大鼠肝微粒体进行化学发光响应研究。
生化／生理作用
硝基还原酶(NTR)可催化还原硝基芳香族底物和醌。NTR的F124K突变体可用于癌症治疗，改善药物CB1954的敏化作用。
硝基还原酶在NADPH或NADH为还原剂的氧还系统中有重要作用。
硝基还原酶增强了生命体对于含氮药物，比如甲硝唑的敏感度，它将氮基团转化为有毒的氮自由基。
能够还原奎宁。 该酶可以激活抗体引导酶前药治疗的前药。
物理性質
含有PBS的冻干粉。 作为辅药不含有BSA
單位定義
在pH7.4、37℃、存在甲萘醌和NADH的条件下，一单位酶每分钟能够还原1μmole细胞色素C。
準備報告
使用没有动物组分的材料生产。
儲存類別代碼
13 - Non Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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