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重要文件

N8381

Sigma-Aldrich

2-萘胺

powder

同義詞:

β-氨基萘, 2-氨基萘

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About This Item

線性公式:
C10H7NH2
CAS號碼:
分子量::
143.19
Beilstein:
3939429
EC號碼:
MDL號碼:
分類程式碼代碼:
12352103
PubChem物質ID:
NACRES:
NA.25

形狀

powder

bp

306 °C (lit.)

mp

111-113 °C (lit.)

密度

1.061 g/mL at 25 °C (lit.)

SMILES 字串

Nc1ccc2ccccc2c1

InChI

1S/C10H9N/c11-10-6-5-8-3-1-2-4-9(8)7-10/h1-7H,11H2

InChI 密鑰

JBIJLHTVPXGSAM-UHFFFAOYSA-N

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一般說明

2-萘胺是一种膀胱癌致癌物,主要存在于香烟烟雾中。

應用

2-萘胺已被用作测定氨肽酶A和氨肽酶N活性的底物。

生化/生理作用

环境致癌物;诱发膀胱癌。

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 1A

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 3

個人防護裝備

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


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分析證明 (COA)

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Y Yasunaga et al.
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Shiho Ohnishi et al.
Japanese journal of cancer research : Gann, 93(7), 736-743 (2002-08-01)
2-Naphthylamine (2-NA), a bladder carcinogen, is contained in cigarette smoke. DNA adduct formation is thought to be a major cause of DNA damage by carcinogenic aromatic amines. We have investigated whether a metabolite of 2-NA, 2-nitroso-1-naphthol (NO-naphthol) causes oxidative DNA
A Fernández-Atucha et al.
Biology of sex differences, 8, 5-5 (2017-02-09)
Serum peptidases, such as angiotensin-converting enzyme (ACE), angiotensin-converting enzyme-2 (ACE2), neutral endopeptidase (NEP), aminopeptidase N (APN), and aminopeptidase A (APA), are important elements of the renin-angiotensin system (RAS). Dysregulation of these enzymes has been associated with hypertension and cardiovascular risk.
Carlos de la Haba et al.
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Receptor-ligand binding is an essential interaction for biological function. Oxidative stress can modify receptors and/or membrane lipid dynamics, thus altering cell physiological functions. The aim of this study is to analyze how oxidative stress may alter receptor-ligand binding and lipid
Carlos de la Haba et al.
Biochimica et biophysica acta, 1828(2), 357-364 (2012-09-04)
Plasma membrane is one of the preferential targets of reactive oxygen species which cause lipid peroxidation. This process modifies membrane properties such as membrane fluidity, a very important physical feature known to modulate membrane protein localization and function. The aim

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US EPA Method 8270 (Appendix IX): GC Analysis of Semivolatiles on Equity®-5 (30 m x 0.25 mm I.D., 0.50 μm)

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