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About This Item
經驗公式（希爾表示法）:
C8H4Cl2N2O2
CAS號碼:
分子量：:
231.04
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77
推薦產品
化驗
≥98% (HPLC)
形狀
solid
顏色
yellow
溶解度
DMSO: 22 mg/mL
儲存溫度
2-8°C
SMILES 字串
O\N=C1\C(=O)Nc2c(Cl)c(Cl)ccc12
InChI
1S/C8H4Cl2N2O2/c9-4-2-1-3-6(5(4)10)11-8(13)7(3)12-14/h1-2,14H,(H,11,12,13)
InChI 密鑰
CVOUSAVHMDXCKG-UHFFFAOYSA-N
生化／生理作用
NS309 is a Ca2+-activated IK/SK potassium channel activator.
特點和優勢
This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
注意
air sensitive
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
Pedarzani, P., et al.
Abstr. Soc. Neurosci, 367-367 (2003)
Jackson T Fontaine et al.
Mechanisms of ageing and development, 192, 111389-111389 (2020-11-01)
Vascular cognitive impairment, the second most common cause of dementia, profoundly affects hippocampal-dependent functions. However, while the growing literature covers complex neuronal interactions, little is known about the sustaining hippocampal microcirculation. Here we examined vasoconstriction to physiological pressures of hippocampal
Fan-Fan Li et al.
Placenta, 58, 9-16 (2017-10-01)
Excessive constriction of placental chorionic plate arteries (CPAs) may be associated with preeclampsia (PE). Nitric oxide (NO) as well as intermediate and small Ca The location of IK IK This study provides evidence that dysregulated IK
Jensen, B.S., et al.
Abstr. Soc. Neurosci, 2003, 367-367 null
Abbie C Johnson et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 37(8), 2857-2869 (2016-11-07)
We investigated the effect of experimental preeclampsia on hyperemia during seizure in the hippocampus and vascular function and structure of hippocampal arterioles using Sprague Dawley rats (n = 14/group) that were nonpregnant, pregnant (d20), or had experimental preeclampsia (induced by a high
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