推薦產品
一般說明
N-亚硝基二乙胺属于亚硝胺类含氮消毒副产物。用氯消毒的水处理设备中也能产生这种副产物。
應用
N-亚硝基二乙胺已用于诱发大鼠和小鼠的肝细胞癌发生。
生化／生理作用
N-亚硝基二乙胺(NDMA)对于所有受试动物物种都是致癌物。主要靶器官是鼻腔、气管、肺、食道和肝脏。NDMA通过作用于细胞色素P450系统而导致致癌物甲基重氮离子的产生。但假单胞菌等微生物可将NDMA代谢为N-硝基甲胺(NTMA)和甲醛。
包裝
批量包装
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 3 Oral - Aquatic Chronic 3 - Carc. 1B
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類（WGK）
WGK 3
個人防護裝備
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
客戶也查看了
Effects of heavy metal ions on N-nitrosodimethylamine (NDMA) formation
Liu Y, et al.
Royal Society of Chemistry Advances, 6(74), 70474-70479 (2016)
Deficiency of pyruvate dehydrogenase kinase 4 sensitizes mouse liver to diethylnitrosamine and arsenic toxicity through inducing apoptosis
Choiniere J, et al.
Liver research, 2(2), 100-107 (2018)
Occurrence and control of N-nitrosodimethylamine in water engineering systems
Bian Y, et al.
Environmental Engineering Research, 24(1), 1-16 (2018)
Smyd3 is a transcriptional potentiator of multiple cancer-promoting genes and required for liver and colon cancer development
Sarris ME, et al.
Cancer Cell, 29(3), 354-366 (2016)
Autophagy-deficient Kupffer cells promote tumorigenesis by enhancing mtROS-NF-kappaB-IL1alphabeta-dependent inflammation and fibrosis during the preneoplastic stage of hepatocarcinogenesis
Sun K, et al.
Cancer letters, 388, 198-207 (2017)
文章
DNA damage and repair mechanism is vital for maintaining DNA integrity. Damage to cellular DNA is involved in mutagenesis, the development of cancer among others.
DNA damage and repair mechanism is vital for maintaining DNA integrity. Damage to cellular DNA is involved in mutagenesis, the development of cancer among others.
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務