推薦產品
用途
sufficient for 100 colorimetric or fluorometric tests
應用
cosmetics
food and beverages
檢測方法
colorimetric
fluorometric
相關疾病
endocrinological disorders, diabetes; cancer
儲存溫度
−20°C
一般說明
L(+)-乳酸是一种通过乳酸脱氢酶的作用而在动物中形成的代谢化合物。乳酸是在增殖的细胞中以及在诸如运动的无氧条件下产生的。 异常高浓度的乳酸与癌症、糖尿病和乳酸酸中毒等病理状况有关。L(+)-乳酸是在人体中间代谢中所形成的乳酸的主要立体异构体,并以约1-2 mmol/L的水平存在于血液中。该试剂盒可提供一种简便的方法用于在生物学样本中进行L(+)-乳酸的检测。无需对样本进行预处理或纯化。
應用
乳酸检测试剂盒已用于确定样本中乳酸的浓度。
適合性
适合用于在培养基、发酵培养基、血液和细胞中检测L(+)-乳酸。
原則
在该测定中,乳酸的浓度是通过一种酶检测而被测定的,其可产生与存在的乳酸成比例的比色(570nm)/荧光测定(λex = 535 nm/λem = 587 nm)产物。该试剂盒的常见灵敏度水平在0.001-10 mM之间。
訊號詞
Danger
危險聲明
危險分類
Resp. Sens. 1 - Skin Sens. 1
儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 3
閃點(°F)
188.6 °F - closed cup
閃點(°C)
87 °C - closed cup
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
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The small-large intestine axis in hydrogen sulfide accumulation and testing of sulfate and lactate in the gut-gut axis of the intestinal environment has not been well described. Sulfate reducing bacteria (SRB) of the Desulfovibrio genus reduce sulfate to hydrogen sulfide
International journal of oncology, 51(2), 498-506 (2017-07-18)
Dichloroacetate (DCA) can reverse the glycolytic phenotype that is responsible of increased lactate production and extracellular pH acidification in cancer cells. Magnetic resonance imaging-chemical exchange saturation transfer (MRI-CEST) pH mapping is a novel non-invasive imaging approach that can measure in vivo
Cardiac STAT3 Deficiency Impairs Contractility and Metabolic Homeostasis in Hypertension.
Frontiers in Pharmacology, 7, 436-436 (2016)
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 47(1), 151-160 (2018-05-16)
Poor response to chemotherapy leads to the relapse and metastatic progression of tumors. Reprogrammed glucose metabolism is one of the important hallmarks of cancer that facilitates cancer cell survival, proliferation and chemoresistance. However, the precise fate of glucose metabolism and
文章
We presents an article about the Warburg effect, and how it is the enhanced conversion of glucose to lactate observed in tumor cells, even in the presence of normal levels of oxygen. Otto Heinrich Warburg demonstrated in 1924 that cancer cells show an increased dependence on glycolysis to meet their energy needs, regardless of whether they were well-oxygenated or not.
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