M8816

来自肝脏的微粒体，合并

from Monkey(Cynomolgus spp.), male

• 同義詞: lab equipment accessory
• 分類程式碼代碼: 12161501
• NACRES: NB.35

屬性

• 生物源: Monkey (Cynomolgus spp.)
• 形狀: liquid
• 比活性: ≥5000 units/mg protein
• 包裝: vial of ~10 mg
• 運輸包裝: dry ice
• 儲存溫度: −70°C

描述

應用

Microsomes from Liver, Pooled has been used to measure the in vitro stabilities of the prodrugs. It has also been used in microsomal incubation to generate BTX-3 metabolites to serve as references for liquid chromatography with tandem mass spectrometry (LC-MS/MS) analyses of urine.

生化／生理作用

肝微粒体是来源于肝细胞内质网的亚细胞颗粒。这些微粒体是药物代谢酶（包括细胞色素 P-450）的丰富来源。不同来源的微粒体池有助于研究外源代谢和药物相互作用。

药物代谢酶的来源，包括细胞色素 P-450。

Microsomal cytochrome P450 proteins can catalyze the transfer of a single oxygen atom to endogenous and exogenous compounds, like steroids and phenobarbital, meant for excretion and detoxification.

單位定義

One unit will produce 1.0 picomole of 6 beta-hydroxytestosterone per minute at pH 7.4 at 37 deg C.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable