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重要文件

M4670

Sigma-Aldrich

D -甘露糖胺 盐酸盐

≥98% (HPLC)

同義詞:

2-氨基-2-脱氧-D-甘露糖 盐酸盐

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About This Item

經驗公式(希爾表示法):
C6H13NO5 · HCl
CAS號碼:
分子量::
215.63
Beilstein:
3914860
EC號碼:
MDL號碼:
分類程式碼代碼:
12352201
PubChem物質ID:
NACRES:
NA.25

生物源

crab (shell)
shrimp shells

品質等級

化驗

≥98% (HPLC)

形狀

powder

技術

HPLC: suitable

顏色

white

mp

168 °C (dec.) (lit.)

溶解度

water: 50 mg/mL, clear, colorless to faintly yellow

儲存溫度

2-8°C

SMILES 字串

Cl[H].N[C@@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O

InChI

1S/C6H13NO5.ClH/c7-3-5(10)4(9)2(1-8)12-6(3)11;/h2-6,8-11H,1,7H2;1H/t2-,3+,4-,5-,6?;/m1./s1

InChI 密鑰

QKPLRMLTKYXDST-OHXGPSCHSA-N

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應用

D-甘露糖胺盐酸盐可用于合成非天然甘露糖类似物,用于在细胞表面唾液酸上表达硫醇。 已用于研究探讨 N-乙酰-β 的合成及高通量筛选-氨基己糖苷酶抑制剂文库靶向骨关节炎。

其他說明

为了全面了解我们针对客户研究提供的各种单糖产品,建议您访问我们的碳水化合物分类页面。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

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Srinivasa-Gopalan Sampathkumar et al.
Nature protocols, 1(5), 2377-2385 (2007-04-05)
The sialic acid biosynthetic pathway in mammalian cells utilizes N-acetyl-D-mannosamine (ManNAc) as a natural metabolic precursor and has the remarkable ability to biosynthetically process non-natural ManNAc analogs. Herein, we describe a recipe-style protocol for the synthesis of the novel peracetylated
Christian M Cole et al.
Chembiochem : a European journal of chemical biology, 14(2), 205-208 (2013-01-08)
Sugar coated: We recently developed methylcyclopropenes as low-molecular-weight tetrazine coupling partners. Here, we demonstrate that methylcyclopropenes can meet the stringent steric demands required for metabolic imaging of unnatural mannosamines on live cells. Using sequential azide-alkyne chemistry, we also demonstrate multicolor
Yasuhiko Iwasaki et al.
Chemical communications (Cambridge, England), 47(37), 10329-10331 (2011-08-20)
In order to obtain cell microarrays formed with human promyelocytic leukemia cells (HL-60), biotinylation of methacryloyl-functionalized HL-60 cells was performed via a thiol-ene reaction with thiol-terminated 4-arm poly(ethylene glycol) (PEG(4)10K-SH). Biotinylated HL-60 cells were selectively adhered onto an avidin-patterned surface
Hesham H Salman et al.
Vaccine, 27(35), 4784-4790 (2009-06-23)
Bioadhesive poly(anhydride) nanoparticles coated with mannose (M-NP) or Salmonella Enteritidis derived flagellin (F-NP) were designed to be applied in oral vaccination strategies using ovalbumin (OVA) as antigen model. Nanoparticles formulations (OVA-M-NP, OVA-F-NP and control OVA-NP) were characterized and evaluated in
Feng Liu et al.
Biochemistry, 48(39), 9194-9201 (2009-09-02)
The Neisseria meningitidis sialic acid synthase (NeuB) catalyzes the metal-dependent condensation of N-acetylmannosamine (ManNAc) and phosphoenolpyruvate (PEP) to generate N-acetylneuraminic acid (NeuAc or sialic acid). N. meningitidis is a causative agent of meningitis and produces a capsular polysaccharide comprised of

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