推薦產品
生物源
synthetic (organic)
化驗
≥93% (HPLC)
形狀
powder
溶解度
water: 50 mg/mL, clear, colorless to faintly brownish-yellow
water: 50 mg/mL, clear, colorless to faintly yellow
water: 50 mg/mL, clear, colorless to very faintly brown
SMILES 字串
[Na].Cc1ccc(Cl)c(Nc2ccccc2C(O)=O)c1Cl
InChI
1S/C14H11Cl2NO2.Na.H/c1-8-6-7-10(15)13(12(8)16)17-11-5-3-2-4-9(11)14(18)19;;/h2-7,17H,1H3,(H,18,19);;
InChI 密鑰
CHGIZYUDGOIAFY-UHFFFAOYSA-N
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一般說明
甲氯芬那酸由两个垂直扭曲的芳基部分组成,它包括N-2,6-二氯-3-甲基苯基和N-2-苯甲酸基团。由于该化合物的水溶性低,因此能够以钠盐的形式出售。
應用
甲氯芬那酸钠盐已被用于:
- 抑制热诱导的白蛋白变性
- 作为药物制剂,制备用于电生理学研究的灌注液
- 阻止间隙连接
生化/生理作用
甲氯芬那酸(MFA)是一种非甾体类抗炎药、镇痛药和解热药。它能够抑制前列腺素的生物合成途径,并且被用于治疗术后以及创伤性炎症和肿胀。MFA在打开电压门控性钾通道Q亚家族成员2/成员3(KCNQ2/Q3)方面发挥作用。
环加氧酶(IC50 = 0.6 μM)和5-脂氧合酶(IC50 = 46.3 μM)抑制剂。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
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