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Key Documents

M4255

Sigma-Aldrich

3-Methoxy-L-tyrosine monohydrate

≥98% (HPLC)

同義詞:

4-Hydroxy-3-methoxy-L-phenylalanine, L-3-O-Methyl-DOPA

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About This Item

經驗公式(希爾表示法):
C10H13NO4 H2O
CAS號碼:
分子量::
229.23
MDL號碼:
分類程式碼代碼:
12352209
PubChem物質ID:
NACRES:
NA.26

product name

3-Methoxy-L-tyrosine monohydrate, powder

化驗

≥98% (HPLC)

品質等級

形狀

powder

應用

detection

儲存溫度

2-8°C

SMILES 字串

COc1cc(C[C@H](N)C(O)=O)ccc1O

InChI

1S/C10H13NO4/c1-15-9-5-6(2-3-8(9)12)4-7(11)10(13)14/h2-3,5,7,12H,4,11H2,1H3,(H,13,14)/t7-/m0/s1

InChI 密鑰

PFDUUKDQEHURQC-ZETCQYMHSA-N

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生化/生理作用

3-Methoxy-L-tyrosine is a metabolite of L-Dopa.
The major metabolite of L-DOPA via catechol O-methyltransferase (COMT). 3-methoxy-L-tyrosine is neither a substrate for nor an inhibitor of L-amino acid decarboxylase activity. Inhibition of COMT enhances the anti-Parkinson activity of L-DOPA.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析證明 (COA)

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Chiara Muzzi et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 62(4), 253-258 (2007-12-26)
Levodopa is the medication of choice for Parkinson's disease. The biological complexity of levodopa and of its main derivatives makes their determination important in the clinical field. The aim of this study was to develop an HPLC method for the

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