M3781

6α-Methylprednisolone 21-hemisuccinate sodium salt

lyophilized powder

• 同義詞: 6α-Methylprednisolone sodium succinate, MPSL, 6α-Methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione 21-hemisuccinate
• 線性公式: C₂₆H₃₃O₈Na
• CAS號碼: 2375-03-3
• 分子量：: 496.53
• EC號碼: 219-156-8
• MDL號碼: MFCD00152612
• 分類程式碼代碼: 12352200
• PubChem物質ID: 24896873
• NACRES: NA.77

屬性

• 生物源: synthetic
• 品質等級: 100
• 無菌: non-sterile
• 化驗: ≥98.00% (TLC)
• 形狀: lyophilized powder
• 技術: toxicology assay: suitable
• 溶解度: water: 50 mg/mL, clear, colorless to faintly yellow
• 運輸包裝: ambient
• 儲存溫度: room temp
• SMILES 字串: [Na+].C[C@H]1CC2C3CC[C@](O)(C(=O)COC(=O)CCC([O-])=O)[C@@]3(C)C[C@H](O)C2[C@@]4(C)C=CC(=O)C=C14
• InChI: 1S/C26H34O8.Na/c1-14-10-16-17-7-9-26(33,20(29)13-34-22(32)5-4-21(30)31)25(17,3)12-19(28)23(16)24(2)8-6-15(27)11-18(14)24;/h6,8,11,14,16-17,19,23,28,33H,4-5,7,9-10,12-13H2,1-3H3,(H,30,31);/q;+1/p-1/t14-,16-,17-,19-,23+,24-,25-,26-;/m0./s1
• InChI 密鑰: FQISKWAFAHGMGT-SGJOWKDISA-M
• 基因資訊: human ... NR3C1(2908)

描述

應用

6α-methylprednisolone 21-hemisuccinate sodium salt has been used to investigate glucocorticoid-induced osteonecrosis under hypoxic conditions in the MC3T3-E1 osteoblast cell line using a cell cytotoxicity assay, flow cytometry and western blotting.

生化／生理作用

Glucocorticoid with slightly longer half-life than that of prednisolone.

外觀

Lyophilized containing ~5% phosphate buffer salts.

安全資訊

• 象形圖: GHS08
• 訊號詞: Danger
• 危險聲明: H351 - H360
• 防範說明: P201 - P308 + P313
• 危險分類: Carc. 2 - Repr. 1B
• 儲存類別代碼: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges