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重要文件

M1275

Sigma-Aldrich

萘普生 钠

98.0-102.0%

同義詞:

(S)-6-甲氧基-α-甲基-2-萘乙酸 钠盐

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About This Item

經驗公式(希爾表示法):
C14H13NaO3
CAS號碼:
分子量::
252.24
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

生物源

synthetic (organic)

品質等級

化驗

98.0-102.0%

形狀

powder

溶解度

water: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow

起源

Bayer

SMILES 字串

[Na+].COc1ccc2cc(ccc2c1)[C@H](C)C([O-])=O

InChI

1S/C14H14O3.Na/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10;/h3-9H,1-2H3,(H,15,16);/q;+1/p-1/t9-;/m0./s1

InChI 密鑰

CDBRNDSHEYLDJV-FVGYRXGTSA-M

基因資訊

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一般說明

萘普生属于苯乙酸类非甾体抗炎药 (NSAID)。

應用

萘普生钠已被用于评价牛血清白蛋白和人血清白蛋白生物分子相互作用的热力学。其也被用于评价其降低脊髓背角神经元对伤害性膝关节旋转反应的效率。

生化/生理作用

萘普生最好与血清白蛋白结合。与 R-异构体相比,萘普生的 S-异构体作为抗炎药物的潜力是前者的 28 倍。发现 R-异构体是一种肝脏毒素,可导致胃肠道疾病。
环加氧酶(前列腺素 H 合成酶 1 和 2)抑制剂。

特點和優勢

该化合物由Bayer开发。要浏览其他药物开发化合物和批准的药物/候选药物列表,单击此处

象形圖

Health hazardExclamation mark

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 4 Oral - Repr. 1A

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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