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來源證明/COA

M0938

7-Methoxycoumarin-4-Acetyl-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys(DNP)-D-Arg-amide

Name: 7-Methoxycoumarin-4-Acetyl-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys(DNP)-<SC>D</SC>-Arg-amide
Brand: SIGMA

>97% (HPLC), solid

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About This Item

經驗公式（希爾表示法）:

C₈₅H₁₂₂N₂₂O₁₉

分子量：:

1756.01

MDL號碼:

MFCD03452962

分類程式碼代碼:

12352200

NACRES:

NA.32

化驗

>97% (HPLC)

形狀

solid

儲存溫度

−20°C

基因資訊

human ... CTSD(1509) , CTSE(1510)
mouse ... CTSD(13033) , CTSE(13034)
rat ... CTSD(171293) , CTSE(25424)

Amino Acid Sequence

MCA-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys-DNP-Arg-NH2

應用

7-methoxycoumarin-4-acetyl-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys-(DNP)-DArg-amide has been used as a fluorogenic substrate for the quantification of cathepsin D in decapod crustaceans.

包裝

Bottomless glass bottle. Contents are inside inserted fused cone.

基底

Substrate for cathepsin D and E.

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

分析證明 (COA)

輸入產品批次/批號來搜索分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。

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Multiple effects of pepstatin A on Trypanosoma cruzi epimastigote forms.

Sangenito LS

Parasitology Research (2012)

Cold-adapted digestive aspartic protease of the clawed lobsters Homarus americanus and Homarus gammarus: biochemical characterization

Liliana Rojo

Marine Biotechnology (2013)

Is digestive cathepsin D the rule in decapod crustaceans?

Diana Martínez-Alarcón et al.

Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 215, 31-38 (2017-10-17)

Cathepsin D is an aspartic endopetidase with typical characteristics of lysosomal enzymes. Cathepsin D activity has been reported in the gastric fluid of clawed lobsters where it acts as an extracellular digestive enzyme. Here we investigate whether cathepsin D is

Characterization of the Temporal Pattern of Blood Protein Digestion in Rhodnius prolixus: First Description of Early and Late Gut Cathepsins.

Bianca Santos Henriques et al.

Frontiers in physiology, 11, 509310-509310 (2021-02-02)

Rhodnius prolixus is one important vector for the parasite Trypanosoma cruzi in Latin America, where Chagas disease is a significant health issue. Although R. prolixus is a model for investigations of vector-parasite interaction and transmission, not much has been done

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