M042030

Biotin Phosphoramidite

configured for ABI

• 同義詞: 生物素酰胺
• 經驗公式（希爾表示法）: C₄₆H₆₄N₅O₈PS
• CAS號碼: 1217500-22-5
• 分子量：: 878.07
• MDL號碼: MFCD00676535
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329817780
• NACRES: NA.21

屬性

• 產品線: Proligo Reagents
• 品質等級: 200
• 化驗: ≥96% (³¹P-NMR)
• 適合性: conforms to structure for H-NMR
• 相容性: configured for ABI
• 儲存溫度: −20°C
• SMILES 字串: COc1ccc(cc1)C(N2C3CS[C@@H](CCCCC(=O)NCCOCCOCCOP(OCCC#N)N(C(C)C)C(C)C)C3NC2=O)(c4ccccc4)c5ccc(OC)cc5
• InChI: 1S/C46H64N5O8PS/c1-34(2)51(35(3)4)60(58-27-12-25-47)59-32-31-57-30-29-56-28-26-48-43(52)16-11-10-15-42-44-41(33-61-42)50(45(53)49-44)46(36-13-8-7-9-14-36,37-17-21-39(54-5)22-18-37)38-19-23-40(55-6)24-20-38/h7-9,13-14,17-24,34-35,41-42,44H,10-12,15-16,26-33H2,1-6H3,(H,48,52)(H,49,53)/t41-,42-,44-,60?/m0/s1
• InChI 密鑰: WSDQYLGSIUJJRU-ZMKGMYJVSA-N

描述

一般說明

Biotin phosphoramidite is a reagent used to directly incorporate a biotin label at the 5′ hydroxy group of the terminal nucleoside base through a p-aminophenethyl spacer group during oligonucleotide synthesis. Biotin-labelled oligonucleotides have become extremely popular in DNAcapture and detection applications, due to their very high-sensitivity and strong, specific binding affinity with avidin and streptavidin proteins. Biotinbased detection methods and are widely used by researchers. Biotin labelling is compatible with PCR and most hybridization techniques.

Key Features of Biotin Phosphoramidite

• Behaves like any standard phosphoramidite on the DNA synthesizer
• Readily soluble in acetonitrile
• Biotin compound has a dimethoxytrityl (DMT) group on the ring structure,which allows coupling-yield determination and trityl-selective purification
• A long, water-compatible linker arm ensures maximum sensitivity
• Provides a coupling efficiency of at least 95%The product is configured for ABI^™ Synthesizers

法律資訊

ABI is a trademark of Applera Corporation or its subsidiaries in the US and/or certain other countries

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable